Evidence map›Paper›PMID 34786106›Full record

ArticleAmerican journal of translational research2021

Comprehensive study of a novel immune-related lncRNA for prognosis and drug treatment of cervical squamous cell carcinoma.

Jinhui Liu, Yinghui Liu, Feng Gao, Jianguo Zhang, Jiadong Pan, Yifei Liu, Hongjun Zhu

Abstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinhui LiuDepartment of Gynecology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, Jiangsu, China.
Yinghui LiuHeilongjiang Institute of Construction Technology Harbin 150025, Heilongjiang, China.
Feng GaoDepartment of Orthopaedics, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, Jiangsu, China.
Jianguo ZhangDepartment of Pathology, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Jiadong PanThe First School of Clinical Medicine, Nanjing Medical University Nanjing 211166, China.
Yifei LiuDepartment of Pathology, Affiliated Hospital of Nantong University Nantong 226001, Jiangsu, China.
Hongjun ZhuDepartment of Oncology, The Third People's Hospital of Nantong Nantong 226001, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A comprehensive study focusing on immune-related long non-coding RNAs (lncRNAs) in cervical cancer (CC) was performed. Through the integration of TCGA data, a total of 266 immune-related lncRNAs were obtained. We defined all samples as an entire set, and randomly divided them into train set and test set at a ratio of 1:1. Univariate, LASSO and multivariate Cox regression analyses were carried out based on train set for key lncRNAs (UBL7-AS1, AC083809.1, LIPE-AS1, PCED1B-AS1, ELFN1-AS1 and NCK1-DT) to construct a prognostic model, while the others were used for validation. The overall survival (OS) suggested that we may have longer survival expectations for patients classified into the low-risk group. The

Indexed as

Cervical cancerimmunityprognostic signaturetherapeutic response

Identifiers

PMID34786106
PMCPMC8581925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.