Evidence map›Paper›PMID 34786039›Full record

ReviewAmerican journal of translational research2021

The pancreas and COVID-19: a clinical conundrum.

Hemant Goyal, Jonathan Kopel, Bojana Ristić, Abhilash Perisetti, Jiannis Anastasiou, Saurabh Chandan, Benjamin Tharian, Sumant Inamdar

Open access · greenAbstract readReview
In one paragraph

Review in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hemant GoyalThe Wright Center for Graduate Medical Education Scranton, PA, USA.
Jonathan KopelDepartment of Medicine, Texas Tech University Health Sciences Center Lubbock, TX, USA.
Bojana RistićCell Biology and Biochemistry, Texas Tech University Health Sciences Center Lubbock, TX, USA.
Abhilash PerisettiDepartment of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences Little Rock, AR, USA.
Jiannis AnastasiouCentral Arkansas Veterans Healthcare System Little Rock, AR, USA.
Saurabh ChandanDivision of Gastroenterology & Hepatology, CHI Creighton University Medical Center Omaha, Nebraska, USA.
Benjamin TharianDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences Little Rock, AR, USA.
Sumant InamdarDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences Little Rock, AR, USA.
University of Arkansas for Medical Sciences · USCHI Health Creighton University Medical Center - Bergan Mercy · USTexas Tech University Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the progression of the COVID-19 pandemic, the classic manifestations of COVID-19 (e.g., persistent fever, dry cough, pneumonia, and acute respiratory distress syndrome in the severe disease) have expanded to include less common complications of the extrapulmonary organs. Recent evidence has shown that COVID-19 patients with concomitant presence of GI symptoms are at higher risk of developing severe disease and have poor clinical outcomes. Recently, multiple SARS-CoV-2-induced acute pancreatitis (AP) cases have been reported. This literature review aims to provide an insight into SARS-CoV-2-directed invasion of the pancreas. We will also review the currently available literature on the clinical effects of SARS-CoV-2, including AP and mild elevation of lipase levels in patients with COVID-19. In addition, we will discuss plausible mechanisms that underly SARS-CoV-2-induced pancreatitis.

Indexed as

amylaseCOVID-19cytokineslipasepancreaspancreatitisSARS-CoV-2

Identifiers

PMID34786039
PMCPMC8581906
OpenAlexW3214372046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.