Evidence map›Paper›PMID 34785884›Full record

ReviewDrug target insights

Serena Losi, Cesare Celeste Federico Berra, Riccardo Fornengo, Dario Pitocco, Giovanni Biricolti, Marco Orsini Federici

Abstract readReview
In one paragraph

Review in Drug target insights. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Routine-data-compatible quality indicators for the ambulatory care of osteoarthritis of the knee and hip: A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Patient preferences in the treatment of children with pollen-related allergic rhinitis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  13. Article
  14. Article
  15. General practice organisational models and heart failure medication adherence: multi-level evidence from a regional cohort in Emilia-Romagna, Italy.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Serena LosiEli Lilly Italy S.p.A., Sesto Fiorentino - Italy.
Cesare Celeste Federico BerraIRCCS MultiMedica, Sesto San Giovanni, Milano - Italy.
Riccardo FornengoS.S.D. di Diabetologia ASL TO4, Torino - Italy.
Dario PitoccoDiabetes Care Unit Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma - Italy.
Giovanni BiricoltiEli Lilly Italy S.p.A., Roma - Italy.
Marco Orsini FedericiEli Lilly Italy S.p.A., Sesto Fiorentino - Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34785884
PMCPMC8591552

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.