Evidence map›Paper›PMID 34785744›Full record

ArticleScientific reports2021

Probing the existence of non-thermal Terahertz radiation induced changes of the protein solution structure.

Martin A Schroer, Siawosch Schewa, Andrey Yu Gruzinov, Christian Rönnau, Janine Mia Lahey-Rudolph, Clement E Blanchet, Till Zickmantel, Young-Hwa Song, Dmitri I Svergun, Manfred Roessle

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Advances in Terahertz Biophysics and Chemistry.Research (Washington, D.C.) · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Martin A SchroerEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation C/O DESY, Notkestr. 85, 22607, Hamburg, Germany. martin.schroer@uni-due.de.
Siawosch SchewaUniversity of Applied Sciences Luebeck, Moenkhofer Weg 239, 23562, Luebeck, Germany.
Andrey Yu GruzinovEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation C/O DESY, Notkestr. 85, 22607, Hamburg, Germany.
Christian RönnauInstitute of Physics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Janine Mia Lahey-RudolphUniversity of Applied Sciences Luebeck, Moenkhofer Weg 239, 23562, Luebeck, Germany.
Clement E BlanchetEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation C/O DESY, Notkestr. 85, 22607, Hamburg, Germany.
Till ZickmantelInstitute of Physics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Young-Hwa SongInstitute of Physics, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.
Dmitri I SvergunEuropean Molecular Biology Laboratory (EMBL), Hamburg Outstation C/O DESY, Notkestr. 85, 22607, Hamburg, Germany.
Manfred RoessleUniversity of Applied Sciences Luebeck, Moenkhofer Weg 239, 23562, Luebeck, Germany.
European Molecular Biology Laboratory · DEUniversity of Lübeck · DE

Funding

Bundesministerium für Bildung und Forschung 05K16YEA
6 · The paper itself

Abstract

During the last decades discussions were taking place on the existence of global, non-thermal structural changes in biological macromolecules induced by Terahertz (THz) radiation. Despite numerous studies, a clear experimental proof of this effect for biological particles in solution is still missing. We developed a setup combining THz-irradiation with small angle X-ray scattering (SAXS), which is a sensitive method for detecting the expected structural changes. We investigated in detail protein systems with different shape morphologies (bovine serum albumin, microtubules), which have been proposed to be susceptible to THz-radiation, under variable parameters (THz wavelength, THz power densities up to 6.8 mW/cm

Indexed as

Terahertz RadiationAnimalsCattleProtein ConformationScattering, Small AngleSerum Albumin, BovineSwineTubulinX-Ray DiffractionSerum Albumin, BovineTubulin

Identifiers

PMID34785744
PMCPMC8595702
OpenAlexW3211775718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.