Evidence map›Paper›PMID 34785692›Full record

ArticleScientific reports2021

A wavelet features derived radiomics nomogram for prediction of malignant and benign early-stage lung nodules.

Rui Jing, Jingtao Wang, Jiangbing Li, Xiaojuan Wang, Baijie Li, Fuzhong Xue, Guangrui Shao, Hao Xue

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Rui Jing *Department of Radiology, Second Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Jingtao Wang *Department of Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, People's Republic of China.
Jiangbing LiDepartment of Cardiology, Shandong Provincial Hospital, Jinan, Shandong, People's Republic of China.
Xiaojuan WangDepartment of Radiology, Second Hospital of Shandong University Zhaoyuan Branch, Zhaoyuan, Shandong, People's Republic of China.
Baijie LiDepartment of Radiology, Second Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Fuzhong XueDepartment of Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, People's Republic of China.
Guangrui ShaoDepartment of Radiology, Second Hospital of Shandong University, Jinan, Shandong, People's Republic of China. 464568603@qq.com.
Hao XueDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China. xuehao@sdu.edu.cn.
Second Hospital of Shandong University · CNShandong University · CNQilu Hospital of Shandong University · CNShandong Provincial Hospital · CN

Funding

Key Research and Development project of Shandong Province 2017G006012 2017G006012National Natural Science Foundation of China 81874083
6 · The paper itself

Abstract

This study was to develop a radiomics nomogram mainly using wavelet features for identifying malignant and benign early-stage lung nodules for high-risk screening. A total of 116 patients with early-stage solitary pulmonary nodules (SPNs) (≤ 3 cm) were divided into a training set (N = 70) and a validation set (N = 46). Radiomics features were extracted from plain LDCT images of each patient. A radiomics signature was then constructed with the LASSO with the training set. Combined with independent risk factors, a radiomics nomogram was built with a multivariate logistic regression model. This radiomics signature, consisting of one original and nine wavelet features, achieved favorable predictive efficacy than Mayo Clinic Model. The radiomics nomogram with radiomics signature and age also showed good calibration and discrimination in the training set (AUC 0.9406; 95% CI 0.8831-0.9982) and the validation set (AUC 0.8454; 95% CI 0.7196-0.9712). The decision curve indicated the clinical usefulness of our nomogram. The presented radiomics nomogram shows favorable predictive accuracy for identifying malignant and benign lung nodules in early-stage patients and is much better than the Mayo Clinic Model.

Indexed as

NomogramsTomography, X-Ray ComputedAdultAgedFemaleHumansLungLung NeoplasmsMaleMiddle AgedRetrospective StudiesSolitary Pulmonary Nodule

Identifiers

PMID34785692
PMCPMC8595377
OpenAlexW3211723907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.