Evidence map›Paper›PMID 34785595›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Posttranscriptional modulation of KCNQ2 gene expression by the miR-106b microRNA family.

Kwon-Woo Kim, Keetae Kim, Hee-Jin Kim, Byeol-I Kim, Myungin Baek, Byung-Chang Suh

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kwon-Woo KimDepartment of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea.ORCID 0000-0003-0449-2172
Keetae KimDepartment of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea; keetae11@gmail.com bcSuh@DGIST.ac.kr.
Hee-Jin KimCenter for Plant Aging Research, Institute for Basic Science, Daegu 42988, Republic of Korea.
Byeol-I KimDepartment of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea.ORCID 0000-0003-4612-0385
Myungin BaekDepartment of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea.
Byung-Chang SuhDepartment of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Republic of Korea; keetae11@gmail.com bcSuh@DGIST.ac.kr.ORCID 0000-0003-0278-2459
Daegu Gyeongbuk Institute of Science and Technology · KRInstitute for Basic Science · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) have recently emerged as important regulators of ion channel expression. We show here that select miR-106b family members repress the expression of the KCNQ2 K

Indexed as

Gene Expression Regulation, NeoplasticAnimalsCell Line, TumorHEK293 CellsHumansKCNQ2 Potassium ChannelMiceMice, Inbred C57BLMicroRNAsNerve Tissue ProteinsNeuronsRatsRats, Sprague-DawleyRNA, MessengerUp-RegulationKCNQ2 Potassium ChannelKCNQ2 protein, humanKcnq2 protein, mouseMicroRNAsMIRN106 microRNA, humanNerve Tissue ProteinsRNA, Messengerdevelopmental regulationKCNQ2/3 K+ channelKCNQ2 proteinmiR-106b familymiRNA

Identifiers

PMID34785595
PMCPMC8617486
OpenAlexW3211547939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.