Evidence map›Paper›PMID 34785520›Full record

ArticleBMJ case reports2021

Complete heart block in neonatal lupus: a forgotten cause of fetal bradycardia.

Sakviseth Bin, Rathmony Heng, Sethikar Im

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sakviseth BinNeonatal Intensive Care Unit, Calmette Hospital, Phnom Penh, Cambodia sakviseth_bin@yahoo.com.ORCID http://orcid.org/0000-0003-2513-8690
Rathmony HengCardiology Department, Calmette Hospital, Phnom Penh, Cambodia.
Sethikar ImNeonatal Intensive Care Unit, Calmette Hospital, Phnom Penh, Cambodia.
Calmette Hospital · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common cause of congenital heart block (CHB) is neonatal lupus, an acquired autoimmune disease caused by transplacental transfer of maternal antibodies to the fetus. A full-term female neonate was admitted to neonatal intensive care unit for severe bradycardia with stable haemodynamics. The mother, showing no clinical symptoms or any particular history, was transferred to our tertiary centre for profound fetal bradycardia. At birth, the infant's ECG showed a third-degree atrioventricular block and echocardiography was normal. Cardiac neonatal lupus was confirmed with positive maternal anti-Ro antibodies. Under close monitoring, the infant tolerated the bradycardia well (median 67 beats per minute (bpm)) and was discharged on day 6 of life. There was no indication for pacemaker, but she would be on regular follow-up with a paediatric cardiologist. This article holds an important insight as it is the first confirmed case of autoimmune CHB in Cambodia in which the mother's antibody was found only after diagnosis on the neonate.

Indexed as

Atrioventricular BlockAutoimmune DiseasesLupus Erythematosus, SystemicBradycardiaChildFemaleHumansInfantInfant, Newbornarrhythmiasimmunologymaterno-fetal medicineneonatal intensive carepregnancy

Identifiers

PMID34785520
PMCPMC8596036
OpenAlexW3213857982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.