ArticleEnvironmental research2022
Exposure to metal mixture and growth indicators at 4-5 years. A study in the INMA-Asturias cohort.
Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Associations of Urinary Lead, Cadmium, and Arsenic Exposure with Obesity-Related Indicators Among School-Aged Children: A Longitudinal Study.Biological trace element research · 2026Article
- The Association of Cadmium Exposure and Anthropometrics in School-Age Children: A Longitudinal Study.Biological trace element research · 2026Article
- Circulating Exosomal MicroRNA Profiles Associated with Heavy Metal Exposure and Short Stature in Children.International journal of molecular sciences · 2026Article
- Early Life Exposure To Multiple Metals, Nutrition, and Growth in Children - A Scoping Review.Current environmental health reports · 2025Article
- Gestational and Early Childhood Exposure to Barium and Cardiometabolic Risk in Preschoolers: Findings From the Ma'anshan Birth Cohort Study in China.Journal of the American Heart Association · 2025Article
- Changes in the Concentration Profile of Selected Micro- and Macro-Elements in the Yellow Ligament Obtained from Patients with Degenerative Stenosis of the Lumbo-Sacral Spine.Journal of clinical medicine · 2025Article
- Exposure to a mixture of four metals and associations with urinary oxidative stress biomarkers in Uruguayan adolescents.Journal of environmental exposure assessment · 2025Article
- A protocol for estimating health burden posed by early life exposure to ambient fine particulate matter and its heavy metal composition: a mother-child birth (ELitE) cohort from Central India.Frontiers in public health · 2025Article
- Evaluation of the Concentration of Selected Elements in the Serum of Patients with Degenerative Stenosis of the Lumbosacral Spine.Biological trace element research · 2024Article
- Urinary metal profiles in mother-offspring pairs and their association with early dysglycemia in the International Hyperglycemia and Adverse Pregnancy Outcome Follow Up Study (HAPO-FUS).Journal of exposure science & environmental epidemiology · 2023Article
- Dietary Exposure to Essential and Non-essential Elements During Infants' First Year of Life in the New Hampshire Birth Cohort Study.Exposure and health · 2023Article
- Dietary Exposure to Toxic Elements and the Health of Young Children: Methodological Considerations and Data Needs.The Journal of nutrition · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundExposure to toxic and non-toxic metals impacts childhood growth and development, but limited data exists on exposure to metal mixtures. Here, we investigated the effects of exposure to individual metals and a mixture of barium, cadmium, cobalt, lead, molybdenum, zinc, and arsenic on growth indicators in children 4-5 years of age.
methodsWe used urine metal concentrations as biomarkers of exposure in 328 children enrolled in the Spanish INMA-Asturias cohort. Anthropometric measurements (arm, head, and waist circumferences, standing height, and body mass index) and parental sociodemographic variables were collected through face-to-face interviews by trained study staff. Linear regressions were used to estimate the independent effects and were adjusted for each metal in the mixture. We applied Bayesian kernel machine regression to examine non-linear associations and potential interactions.
resultsIn linear regression, urinary levels of cadmium were associated with reduced arm circumference (β
conclusionOur findings suggest that exposure to metal mixtures impacts growth indicators in children.
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