Observational study in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 4 institutions in 1 country.
Fu-Ying TianGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Elizabeth M KennedyGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Karen HermetzGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Amber BurtGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-1813-6726
Todd M EversonGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Tracy PunshonDepartment of Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA.ORCID 0000-0003-0782-446X
Brian P JacksonDepartment of Earth Sciences, Dartmouth College, Hanover, New Hampshire, USA.
Ke HaoDepartment of Genetics and Genome Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jia ChenDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.ORCID 0000-0002-6398-7362
Devin C KoestlerThe University Kansas Cancer Center, The University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0002-0598-0146
Carmen MarsitGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-4566-150X
Emory University · USDartmouth College · USIcahn School of Medicine at Mount Sinai · USThe University of Kansas Cancer Center · US
Funding
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI CHRISTENSEN, BROCK CLARKE · 2013 to 2022
$23.7M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2013 to 2018
$4.7M
Influence of prenatal psychosocial stressors on maternal and fetal circulating miRNAsR01MD011698 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN, MARSIT, CARMEN JOSEPH · 2017 to 2021
$3.3M
Enriching the Rhode Island Child Health StudyR24ES028507 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit, LAURA R STROUD · 2017 to 2026
$2.3M
MicroRNA, Environmental Exposures and Newborn OutcomesR01ES025145 · NIEHS · EMORY UNIVERSITY · PI KOESTLER, DEVIN CHARLES, MARSIT, CARMEN JOSEPH · 2016 to 2019
$1.8M
Placental and breastmilk microRNAs in relation to early-life growth and metabolismK99HD104991 · NICHD · EMORY UNIVERSITY · PI GOEHRING, ELIZABETH MARIE KENNEDY · 2021 to 2022
Selenium is an important micronutrient for foetal development. MicroRNAs play an important role in the function of the placenta, in communication between the placenta and maternal systems, and their expression can be altered through environmental and nutritional cues. To investigate the associations between placental selenium concentration and microRNA expression in the placenta, our observational study included 393 mother-child pairs from the New Hampshire Birth Cohort Study (NHBCS) and the Rhode Island Child Health Study (RICHS). Placental selenium concentrations were quantified using inductively coupled plasma mass spectrometry, and microRNA transcripts were measured using RNA-seq. We fit negative binomial additive models for assessing the association between selenium and microRNAs. We used the microRNA Data Integration Portal (mirDIP) to predict the target mRNAs of the differentially expressed microRNAs and verified the relationships between miRNA and mRNA targets in a subset of samples using existing whole transcriptome data (N = 199). We identified a non-monotonic association between selenium concentration and the expression of miR-216a-5p/miR-217-5p cluster (effective degrees of freedom, EDF = 2.44 and 2.08; FDR = 3.08 × 10
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Selenium-associated differentially expressed microRNAs and their targeted mRNAs across the placental genome in two U.S. birth cohorts. · full record | OpenQuestion