Evidence map›Paper›PMID 34784815›Full record

ArticleJournal of attention disorders2022

Cognitive and Neuroimaging Profiles of Older Adults With Attention Deficit/Hyperactivity Disorder Presenting to a Memory Clinic.

Brandy L Callahan, Nayani Ramakrishnan, Prathiba Shammi, Daniel Bierstone, Rebecca Taylor, Miracle Ozzoude, Maged Goubran, Donald T Stuss, Sandra E Black

Open access · hybridAbstract read
In one paragraph

Article in Journal of attention disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Association Between the Genetic Risk for Attention-Deficit/Hyperactivity Disorder and Cognitive Function in Older Age: The MYHAT Population-Based Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Brandy L CallahanUniversity of Calgary, Calgary, AB, Canada.ORCID 0000-0001-5617-2379
Nayani RamakrishnanUniversity of Toronto, Toronto, ON, Canada.
Prathiba ShammiUniversity of Toronto, Toronto, ON, Canada.
Daniel BierstoneUniversity of Toronto, Toronto, ON, Canada.
Rebecca TaylorUniversity of Toronto, Toronto, ON, Canada.
Miracle OzzoudeUniversity of Toronto, Toronto, ON, Canada.
Maged GoubranUniversity of Toronto, Toronto, ON, Canada.
Donald T StussUniversity of Toronto, Toronto, ON, Canada.
Sandra E BlackUniversity of Toronto, Toronto, ON, Canada.
University of Toronto · CAUniversity of Calgary · CA

Funding

CIHR FDN 159910CIHR MOP-13129
6 · The paper itself

Abstract

objectiveSome features of attention-deficit/hyperactivity disorder (ADHD) may resemble those of mild cognitive impairment (MCI) in older adults, contributing to diagnostic uncertainty in individuals seeking assessment in memory clinics. We systematically compared cognition and brain structure in ADHD and MCI to clarify the extent of overlap and identify potential features unique to each.

methodOlder adults from a Cognitive Neurology clinic (40 ADHD, 29 MCI, 37 controls) underwent neuropsychological assessment. A subsample (

resultsMemory was impaired in both patient groups, but reflected a storage deficit in MCI (supported by relatively smaller hippocampi) and an encoding deficit in ADHD (supported by frontal lobe thinning). Both groups displayed normal executive functioning. Semantic retrieval was uniquely impaired in MCI.

conclusionAlthough ADHD has been proposed as a dementia risk factor or prodrome, we propose it is rather a pathophysiologically-unique phenotypic mimic acting via overlap in memory and executive performance.

Indexed as

Attention Deficit Disorder with HyperactivityAgedCognitionExecutive FunctionHumansNeuroimagingNeuropsychological TestsADDattention-deficit disorderdementialanguageMRIneuropsychology

Identifiers

PMID34784815
PMCPMC9066671
OpenAlexW3213807518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.