Evidence map›Paper›PMID 34784353›Full record

ArticlePLoS computational biology2021

A nowcasting framework for correcting for reporting delays in malaria surveillance.

Tigist F Menkir, Horace Cox, Canelle Poirier, Melanie Saul, Sharon Jones-Weekes, Collette Clementson, Pablo M de Salazar, Mauricio Santillana, Caroline O Buckee

Open access · goldAbstract read
In one paragraph

Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Ensemble approaches for short-term dengue fever forecasts: A global evaluation study.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tigist F MenkirCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.
Horace CoxVector Control Services, Ministry of Public Health, Georgetown, Guyana.
Canelle PoirierComputational Health Informatics Program, Boston Children's Hospital, Boston Massachusetts, United States of America.ORCID 0000-0002-6972-2621
Melanie SaulVector Control Services, Ministry of Public Health, Georgetown, Guyana.ORCID 0000-0001-6003-7006
Sharon Jones-WeekesVector Control Services, Ministry of Public Health, Georgetown, Guyana.
Collette ClementsonVector Control Services, Ministry of Public Health, Georgetown, Guyana.
Pablo M de SalazarCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.ORCID 0000-0002-8096-2001
Mauricio SantillanaCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.
Caroline O BuckeeCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.ORCID 0000-0002-8386-5899
University of Guyana · GYCenter for Disease Dynamics, Economics & Policy · USBoston Children's Hospital · US

Funding

Understanding and controlling antibiotic resistanceU54GM088558 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LIPSITCH, MARC · 2009 to 2018
$26.4M
New approaches to measuring and containing the spatial spread of human pathogensR35GM124715 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BUCKEE, CAROLINE O'FLAHERTY · 2017 to 2021
$2.0M
Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease ActivityR01GM130668 · NIGMS · NORTHEASTERN UNIVERSITY · PI SANTILLANA, MAURICIO · 2018 to 2022
$1.9M
NIGMS NIH HHS R01 GM130668NIGMS NIH HHS R35 GM124715NIGMS NIH HHS U54 GM088558
6 · The paper itself

Abstract

Time lags in reporting to national surveillance systems represent a major barrier for the control of infectious diseases, preventing timely decision making and resource allocation. This issue is particularly acute for infectious diseases like malaria, which often impact rural and remote communities the hardest. In Guyana, a country located in South America, poor connectivity among remote malaria-endemic regions hampers surveillance efforts, making reporting delays a key challenge for elimination. Here, we analyze 13 years of malaria surveillance data, identifying key correlates of time lags between clinical cases occurring and being added to the central data system. We develop nowcasting methods that use historical patterns of reporting delays to estimate occurred-but-not-reported monthly malaria cases. To assess their performance, we implemented them retrospectively, using only information that would have been available at the time of estimation, and found that they substantially enhanced the estimates of malaria cases. Specifically, we found that the best performing models achieved up to two-fold improvements in accuracy (or error reduction) over known cases in selected regions. Our approach provides a simple, generalizable tool to improve malaria surveillance in endemic countries and is currently being implemented to help guide existing resource allocation and elimination efforts.

Indexed as

Population SurveillanceGuyanaHumansMalariaModels, StatisticalRetrospective Studies

Identifiers

PMID34784353
PMCPMC8659367
OpenAlexW3213784469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.