Evidence map›Paper›PMID 34784324›Full record

ArticleAnesthesia and analgesia2021

Impact of Neuraxial Versus General Anesthesia on Discharge Destination in Patients Undergoing Primary Total Hip and Total Knee Replacement.

Melissa Duque, Michael P Schnetz, Adolph J Yates, Amanda Monahan, Steven Whitehurst, Aman Mahajan, A Murat Kaynar

2 registry-linked trialsOpen access · greenAbstract readComparative Study
In one paragraph

Article in Anesthesia and analgesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05916209 completednot on this mapstarted 2023, after this paper: background citation

Pericapsular Nerve Group (PENG) Block and Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca (FIC) Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis

TypeobservationalSponsorOspedale Edoardo BassiniRan2023 to 2023Enrolled60ConditionsRegional Anesthesia Morbidity, Arthropathy of Hip, Hip ArthropathyArmsPeripheral nerve blocks
NCT07334132 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty

TypeinterventionalSponsorRegion Örebro CountyRan2026 to 2029Enrolled600ConditionsOsteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)ArmsGeneral Anaesthesia, Spinal Anesthesia (bupivacaine)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Melissa DuqueFrom the Departments of Anesthesiology and Perioperative Medicine.
Michael P SchnetzFrom the Departments of Anesthesiology and Perioperative Medicine.
Adolph J YatesOrthopaedic Surgery.
Amanda MonahanFrom the Departments of Anesthesiology and Perioperative Medicine.
Steven WhitehurstFrom the Departments of Anesthesiology and Perioperative Medicine.
Aman MahajanFrom the Departments of Anesthesiology and Perioperative Medicine.
A Murat KaynarFrom the Departments of Anesthesiology and Perioperative Medicine.
University of Pittsburgh · US

Funding

Combined viral and bacterial infection and zinc homeostasis in distal lungR01HL126711 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAYNAR, A. MURAT · 2015 to 2019
$2.0M
NHLBI NIH HHS R01 HL126711
6 · The paper itself

Abstract

backgroundTotal knee replacement (TKR) and total hip replacement (THR) are 2 of the most common orthopedic surgical procedures in the United States. These procedures, with fairly low mortality rates, incur significant health care costs, with almost 40% of the costs associated with post acute care. We assessed the impact of general versus neuraxial anesthesia on discharge destination and 30-day readmissions in patients who underwent total knee and hip replacement in our health system.

methodsThis was a retrospective cohort study of 24,684 patients undergoing total knee or hip replacement in 13 hospitals of a large health care network. Following propensity score matching, we studied the impact of type of anesthetic technique on discharge destination (primary outcome) and postoperative complications including readmissions in 8613 patients who underwent THR and 13,004 patients for TKR.

resultsOur results showed that in patients undergoing THR and TKR, neuraxial anesthesia is associated with higher odds of being discharged from hospital to home versus other facilities compared to general anesthesia (odds ratio [OR] = 1.63, 95% confidence interval [CI], 1.52-1.76; P < .01) and (OR = 1.58, 95% CI, 1.49-1.67; P < .01), respectively.

conclusionsOur results suggest an association between use of neuraxial anesthesia for total joint arthroplasty and a higher probability of discharge to home and a reduction in readmissions.

Indexed as

AgedAged, 80 and overAnesthesia, ConductionAnesthesia, GeneralArthroplasty, Replacement, HipArthroplasty, Replacement, KneeCohort StudiesFemaleHumansMaleMiddle AgedPatient DischargePatient ReadmissionPostoperative ComplicationsPropensity ScoreRetrospective Studies

Identifiers

PMID34784324
PMCPMC8604382
OpenAlexW3213458270

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.