Evidence map›Paper›PMID 34784052›Full record

ReviewPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2022

Latest trends on photodynamic disinfection of Gram-negative bacteria: photosensitizer's structure and delivery systems.

Nidia Maldonado-Carmona, Tan-Sothea Ouk, Stéphanie Leroy-Lhez

Abstract readReview
PubMed Publisher
In one paragraph

Review in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Enhanced photodynamic disruption of multidrug-resistantBiochemistry and biophysics reports · 2025
    Article
  3. Article
  4. CuAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Bio-based matrix photocatalysts for photodegradation of antibiotics.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Review
  8. Article
  9. Metals to combat antimicrobial resistance.Nature reviews. Chemistry · 2023
    Review
  10. Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA- and PVA-chitosan-based electrospun nanomaterials cross-linked with tailor-made silicon(IV) phthalocyanine.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Nidia Maldonado-CarmonaPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060, Limoges, France.
Tan-Sothea OukPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060, Limoges, France.
Stéphanie Leroy-LhezPEIRENE Laboratory, Faculty of Sciences and Techniques, University of Limoges, 87060, Limoges, France. stephanie.lhez@unilim.fr.ORCID http://orcid.org/0000-0002-6933-1372
Université de Limoges · FR

Funding

h2020 marie skłodowska-curie actions 764837
6 · The paper itself

Abstract

Antimicrobial resistance is threatening to overshadow last century's medical advances. Etiological agents of previously eradicated infectious diseases are now resurgent as multidrug-resistant strains, especially for Gram-negative strains. Finding new therapeutic solutions is a real challenge for our society. In this framework, Photodynamic Antimicrobial ChemoTherapy relies on the generation of toxic reactive oxygen species in the presence of light, oxygen, and a photosensitizer molecule. The use of reactive oxygen species is common for disinfection processes, using chemical agents, such as chlorine and hydrogen peroxide, and as they do not have a specific molecular target, it decreases the potential of tolerance to the antimicrobial treatment. However, light-driven generated reactive species result in an interesting alternative, as reactive species generation can be easily tuned with light irradiation and several PSs are known for their low environmental impact. Over the past few years, this topic has been thoroughly studied, exploring strategies based on single-molecule PSs (tetrapyrrolic compounds, dipyrrinate derivatives, metal complexes, etc.) or on conjunction with delivery systems. The present work describes some of the most relevant advances of the last 6 years, focusing on photosensitizers design, formulation, and potentiation, aiming for the disinfection of Gram-negative bacteria.

Indexed as

PhotochemotherapyPhotosensitizing AgentsAnti-Bacterial AgentsDisinfectionGram-Negative BacteriaAnti-Bacterial AgentsPhotosensitizing AgentsAntibacterial alternativesDelivery systemsDisinfectionPhotosensitizers

Identifiers

PMID34784052
OpenAlexW3214370040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.