Evidence map›Paper›PMID 34783647›Full record

ArticleMicrobial genomics2021

Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation in

Emma R Holden, Muhammad Yasir, A Keith Turner, John Wain, Ian G Charles, Mark A Webber

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  13. Identification of pathways required forApplied and environmental microbiology · 2024
    Article
  14. UropathogenicMicroorganisms · 2023
    Review
  15. Article
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emma R HoldenQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
Muhammad YasirQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
A Keith TurnerQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
John WainQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
Ian G CharlesQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
Mark A WebberQuadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk NR4 7UQ, UK.
Norwich Research Park · GBUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R012504/1Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10349
6 · The paper itself

Abstract

Biofilms complete a life cycle where cells aggregate, grow and produce a structured community before dispersing to colonize new environments. Progression through this life cycle requires temporally controlled gene expression to maximize fitness at each stage. Previous studies have largely focused on identifying genes essential for the formation of a mature biofilm; here, we present an insight into the genes involved at different stages of biofilm formation. We used TraDIS-

Indexed as

Escherichia coli InfectionsEscherichia coli ProteinsBiofilmsEscherichia coliGenes, EssentialHumansMutagenesisdksA protein, E coliEscherichia coli Proteinsadhesionfunctional genomicsTraDIS

Identifiers

PMID34783647
PMCPMC8743551
OpenAlexW3213914872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.