Evidence map›Paper›PMID 34783553›Full record

ArticleJournal of chemical information and modeling2021

COVID-19 Knowledge Extractor (COKE): A Curated Repository of Drug-Target Associations Extracted from the CORD-19 Corpus of Scientific Publications on COVID-19.

Daniel Korn, Vera Pervitsky, Tesia Bobrowski, Vinicius M Alves, Charles Schmitt, Chris Bizon, Nancy Baker, Rada Chirkova, Artem Cherkasov, Eugene Muratov and 1 more

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Daniel KornDepartment of Computer Science, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Vera PervitskyLaboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Tesia BobrowskiLaboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Vinicius M AlvesOffice of Data Science, National Toxicology Program, NIEHS, Morrisville, North Carolina 27560, United States.ORCID 0000-0002-6182-1748
Charles SchmittOffice of Data Science, National Toxicology Program, NIEHS, Morrisville, North Carolina 27560, United States.
Chris BizonRenaissance Computing Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Nancy BakerParlezChem, 123 W. Union Street, Hillsborough, North Carolina 27278, United States.
Rada ChirkovaDepartment of Computer Science, North Carolina State University, Raleigh, North Carolina 27606-5550, United States.
Artem CherkasovVancouver Prostate Centre, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.
Eugene MuratovLaboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-4616-7036
Alexander TropshaLaboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-3802-8896

Funding

ARAGORN: Autonomous Relay Agent for Generation Of Ranked NetworksOT2TR003441 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TROPSHA, ALEXANDER · 2020 to 2024
$4.7M
Development of Data Science MethodsZIAES103364 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SCHMITT, CHARLES · 2021 to 2025
$1.6M
Intramural NIH HHS ZIA ES103364
6 · The paper itself

Abstract

The COVID-19 pandemic has catalyzed a widespread effort to identify drug candidates and biological targets of relevance to SARS-COV-2 infection, which resulted in large numbers of publications on this subject. We have built the

Indexed as

COVID-19Pharmaceutical PreparationsAntiviral AgentsDrug RepositioningHumansPandemicsSARS-CoV-2Antiviral AgentsPharmaceutical Preparations

Identifiers

PMID34783553
PMCPMC13138251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.