Evidence map›Paper›PMID 34783397›Full record

ArticleClinical transplantation2022

Psychosocial characteristics of patients evaluated for kidney transplant and associations with functional and frailty metrics at a veterans affairs hospital.

Priyadarshini Manay, Patrick Ten Eyck, Erin Siniff, Grace Binns, M Lee Sanders, Melissa Swee, Jodell L Hornickel, Roberto Kalil, Daniel A Katz

Abstract read
In one paragraph

Article in Clinical transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Priyadarshini ManayDepartment of Surgery, Organ Transplant Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0003-0026-7146
Patrick Ten EyckInstitute for Clinical and Translational Science, University of Iowa, Iowa City, Iowa.ORCID 0000-0002-5041-0708
Erin SiniffVeterans Affairs Medical Center, Iowa City, Iowa, USA.
Grace BinnsVeterans Affairs Medical Center, Iowa City, Iowa, USA.ORCID 0000-0001-9442-3757
M Lee SandersVeterans Affairs Medical Center, Iowa City, Iowa, USA.ORCID 0000-0002-5968-9899
Melissa SweeVeterans Affairs Medical Center, Iowa City, Iowa, USA.ORCID 0000-0002-1591-0862
Jodell L HornickelVeterans Affairs Medical Center, Iowa City, Iowa, USA.
Roberto KalilDepartment of Medicine, University of Maryland Medical Center and Veterans Affairs Medical Center, Baltimore, Maryland, USA.
Daniel A KatzDepartment of Surgery, Organ Transplant Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID 0000-0002-6495-0078

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
NCATS NIH HHS UL1 TR002537
6 · The paper itself

Abstract

backgroundThe effect of psychosocial problems on listing outcomes and potential interactions with functional metrics is not well-characterized among Veteran transplant candidates.

methodsThe results from psychosocial evaluations, frailty metrics, and biochemical markers were collected on 375 consecutive Veteran kidney transplant candidates. Psychosocial diagnoses were compared between patients listed or denied for transplant. Functional abilities were compared among patients with or without psychosocial diagnoses and then evaluated based on reason for denial.

resultsEighty-four percent of patients had a psychosocial diagnosis. Common issues included substance or alcohol abuse (62%), psychiatric diagnoses (50%), and poor adherence (25%). Patients with psychiatric diagnoses, cognitive impairments, and poor adherence were more likely to be denied for transplant (P < .05). Patients with depression, PTSD, and anxiety did not have worse functional ability, but experienced more exhaustion than patients without these problems. Patients denied for medical but not purely psychosocial reasons had worse troponin and functional metrics compared with listed patients.

conclusionOver 80% of patients with a psychosocial diagnosis were listed; however, poor adherence was a particularly important reason for denial for purely psychosocial reasons. Patients with psychosocial diagnoses generally were not more functionally limited than their counterparts without psychosocial diagnoses or those listed for transplant.

Indexed as

FrailtyKidney TransplantationVeteransBenchmarkingHospitalsHumansdepressionfrailtykidney transplant evaluationlisting outcomesmodelsnonadherencepedometerpsychosocialtreadmillup-and-go

Identifiers

PMID34783397
PMCPMC10305838

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.