ArticleBiochemical Society transactions2021
Chromosome clustering in mitosis by the nuclear protein Ki-67.
Article in Biochemical Society transactions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Spindle pole proteins confine chromosomes to ensure their expulsion during female meiosis.bioRxiv : the preprint server for biology · 2026Article
- Expression characteristics and detection value of Ki67, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2) in patients with breast cancer.Pakistan journal of medical sciences · 2026Article
- Light-modulated stem cells in the camera-type eye of an annelid model for adult brain plasticity.Nature communications · 2025Article
- The mitotic chromosome periphery modulates chromosome mechanics.Nature communications · 2025Article
- Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes.Journal of lipid research · 2025Article
- Ki-67 is necessary during DNA replication for fork protection and genome stability.Genome biology · 2024Article
- Between Centralization and Fragmentation: The Past, Present, and Future of Phage Collections.PHAGE (New Rochelle, N.Y.) · 2024Review
- Review
- CCDC86 is a novel Ki-67-interacting protein important for cell division.Journal of cell science · 2023Article
- Dephosphorylation in nuclear reassembly after mitosis.Frontiers in cell and developmental biology · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Ki-67 is highly expressed in proliferating cells, a characteristic that made the protein a very important proliferation marker widely used in the clinic. However, the molecular functions and properties of Ki-67 remained quite obscure for a long time. Only recently important discoveries have shed some light on its function and shown that Ki-67 has a major role in the formation of mitotic chromosome periphery compartment, it is associated with protein phosphatase one (PP1) and regulates chromatin function in interphase and mitosis. In this review, we discuss the role of Ki-67 during cell division. Specifically, we focus on the importance of Ki-67 in chromosome individualisation at mitotic entry (prometaphase) and its contribution to chromosome clustering and nuclear remodelling during mitotic exit.
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Registered trials
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