Evidence map›Paper›PMID 34783218›Full record

Observational studyJournal of Korean medical science2021

Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study.

Ali Eman, Onur Balaban, Havva Kocayiğit, Kezban Özmen Süner, Y Cırdı, Ali Fuat Erdem

Open access · goldAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Risk factors and outcomes of critically ill pregnant COVID-19 patients: Experience from the first and second waves of the pandemic.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  3. Article
  4. Review
  5. Observational
  6. Observational
  7. Article
  8. Article
  9. Perinatal outcomes of pregnant women with COVID-19.Taiwanese journal of obstetrics & gynecology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ali EmanDepartment of Anesthesiology and Reanimation, Sakarya Training and Research Hospital, Sakarya, Turkey. dralieman02@gmail.com.ORCID https://orcid.org/0000-0001-7251-1828
Onur BalabanDepartment of Anesthesiology and Reanimation, Sakarya University Faculty of Medicine, Training and Research Hospital, Sakarya, Turkey.ORCID https://orcid.org/0000-0003-0953-4191
Havva KocayiğitDepartment of Anesthesiology and Reanimation, Sakarya Training and Research Hospital, Sakarya, Turkey.ORCID https://orcid.org/0000-0002-8719-7031
Kezban Özmen SünerDepartment of Intensive Care, Sakarya Training and Research Hospital, Sakarya, Turkey.ORCID https://orcid.org/0000-0002-9822-4031
Y CırdıDepartment of Intensive Care, Sakarya Training and Research Hospital, Sakarya, Turkey.ORCID https://orcid.org/0000-0002-0258-2441
Ali Fuat ErdemDepartment of Anesthesiology and Reanimation, Sakarya University Faculty of Medicine, Training and Research Hospital, Sakarya, Turkey.ORCID https://orcid.org/0000-0003-0821-5500
Sakarya Eğitim ve Araştırma Hastanesi · TRSakarya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed maternal and neonatal outcomes of critically ill pregnant and puerperal patients in the clinical course of coronavirus disease 2019 (COVID-19).

methodsRecords of pregnant and puerperal women with polymerase chain reaction positive COVID-19 virus who were admitted to our intensive care unit (ICU) from March 2020 to August 2021 were investigated. Demographic, clinical and laboratory data, pharmacotherapy, and neonatal outcomes were analyzed. These outcomes were compared between patients that were discharged from ICU and patients who died in ICU.

resultsNineteen women were included in this study. Additional oxygen was required in all cases (100%). Eight patients (42%) were intubated and mechanically ventilated. All patients that were mechanically ventilated have died. Increased levels of C-reactive protein (CRP) was seen in all patients (100%). D-dimer values increased in 15 patients (78.9%); interleukin-6 (IL-6) increased in 16 cases (84.2%). Sixteen patients used antiviral drugs. Eleven patients were discharged from the ICU and eight patients have died due to complications of COVID-19 showing an ICU mortality rate of 42.1%. Mean number of hospitalized days in ICU was significantly lower in patients that were discharged (

conclusionHigh mortality rate was detected among critically ill pregnant/parturient patients followed in the ICU. Main predictors of mortality were the need of invasive mechanical ventilation and higher number of days hospitalized in ICU. Rate of C/S operations and preterm delivery were high. Pleasingly, the rate of neonatal death was low and no neonatal COVID-19 occurred.

Indexed as

SARS-CoV-2AdultAntiviral AgentsCesarean SectionCombined Modality TherapyCOVID-19Critical IllnessDelivery, ObstetricFemaleHospital MortalityHumansInfant, NewbornIntensive Care UnitsLength of StayLungOxygen Inhalation TherapyAntiviral AgentsClinical OutcomeCOVID-19Critical IllPregnancyPuerperiumSARS-CoV-2

Identifiers

PMID34783218
PMCPMC8593409
OpenAlexW3213457557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.