Evidence map›Paper›PMID 34783055›Full record

SynthesisJournal of medical virology2022

Postvaccination SARS-CoV-2 infection among healthcare workers: A systematic review and meta-analysis.

Saurabh Chandan, Shahab R Khan, Smit Deliwala, Babu P Mohan, Daryl Ramai, Ojasvini C Chandan, Antonio Facciorusso

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. SARS-CoV-2 anti-N antibodies among healthcare personnel without previous known COVID-19.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  10. Observational
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Review
  16. COVID-19 as an Occupational Disease-Temporal Trends in the Number and Severity of Claims in Germany.International journal of environmental research and public health · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Evaluation of the effect ofFrontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saurabh ChandanDivision of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, Nebraska, USA.ORCID http://orcid.org/0000-0002-2661-6693
Shahab R KhanDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Smit DeliwalaDepartment of Internal Medicine, Internal Medicine, Hurley Medical Center, Flint, Michigan, USA.
Babu P MohanDivision of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Daryl RamaiDivision of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Ojasvini C ChandanDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Omaha, Omaha, Nebraska, USA.
Antonio FacciorussoDepartment of Surgical and Medical Sciences, Gastroenterology Unit, University of Foggia, Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare workers (HCWs) remain on the front line of the battle against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) infection and are among the highest groups at risk of infection during this raging pandemic. We conducted a systematic review and meta-analysis to assess the incidence of postvaccination SARS-CoV-2 infection among vaccinated HCWs. We searched multiple databases from inception through August 2021 to identify studies that reported on the incidence of postvaccination SARS-CoV-2 infection among HCWs. Meta-analysis was performed to determine pooled proportions of COVID-19 infection in partially/fully vaccinated as well as unvaccinated individuals. Eighteen studies with 228 873 HCWs were included in the final analysis. The total number of partially vaccinated, fully vaccinated, and unvaccinated HCWs were 132 922, 155 673, and 17 505, respectively. Overall pooled proportion of COVID-19 infections among partially/fully vaccinated and unvaccinated HCWs was 2.1% (95% confidence interval [CI] 1.2-3.5). Among partially vaccinated, fully vaccinated and unvaccinated HCWs, pooled proportion of COVID-19 infections was 2.3% (CI 1.2-4.4), 1.3% (95% CI 0.6-2.9), and 10.1% (95% CI 4.5-19.5), respectively. Our analysis shows the risk of COVID-19 infection in both partially and fully vaccinated HCWs remains exceedingly low when compared to unvaccinated individuals. There remains an urgent need for all frontline HCWs to be vaccinated against SARS-CoV-2 infection.

Indexed as

SARS-CoV-2COVID-19COVID-19 VaccinesHealth PersonnelHumansIncidenceVaccinationCOVID-19 VaccinesCOVID-19healthcare workersvaccine

Identifiers

PMID34783055
PMCPMC8661690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.