ArticleReproductive sciences (Thousand Oaks, Calif.)2022
Male Age and Progressive Sperm Motility Are Critical Factors Affecting Embryological and Clinical Outcomes in Oocyte Donor ICSI Cycles.
Article in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Does paternal age affect the live birth rate in donor oocyte cycles? A systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2023Pooled it
- Fertility in the aging male: a systematic review.Fertility and sterility · 2022Pooled it
- Nomogram models to predict low fertilisation rate and total fertilisation failure in patients undergoing conventional IVF cycles.BMJ open · 2022Trial
- Combined effects of urine exposure and cryopreservation on sperm quality: an in vitro study of retrograde ejaculation.Asian journal of andrology · 2026Article
- Intraoperative epididymal sperm cryopreservation during microsurgical vasoepididymostomy for obstructive azoospermia: intracytoplasmic sperm injection outcomes from a single-center cohort.Translational andrology and urology · 2026Article
- Clinical Implications of Paternal Age in Assisted Reproduction: Integrating Sperm Epigenetic Evidence.Journal of clinical medicine · 2026Review
- An Artificial Intelligence-Based Computer Vision Model for Human Sperm Concentration, Motility, and Kinematics Analysis.Smart medicine · 2026Article
- Acute stress induction downregulates RHOX-5 gene expression causing altered fertility indices in MALE Wistar rats.JBRA assisted reproduction · 2026Article
- Nanostructured lipid carriers for L-carnitine delivery: physicochemical characterization and effects on asthenozoospermic sperm function in vitro.Scientific reports · 2025Article
- Article
- Analysis of related factors of biochemical pregnancy loss in single blastocyst transfer in the hormone replacement protocol frozen-thawed cycle.BMC pregnancy and childbirth · 2025Article
- A WHO 2021-based comprehensive scheme outlining sperm parameters' associations with IVF outcomes in PGT-A cycles.Andrology · 2025Article
- Impact of cryopreservation agents on sperm quality, DNA fragmentation, and apoptotic markers in fertile and infertile males.Scientific reports · 2025Article
- Impact of Male Age and Semen Parameters on Blastocyst Morphology, Beta-HCG Positivity and Pregnancy Viability: A Retrospective Analysis in Frozen Embryo Transfer Cycles.Journal of obstetrics and gynaecology of India · 2025Article
- Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025Review
- Obesity and male infertility - a tenuous relationship: Facts discerned for the busy clinicians.Arab journal of urology · 2025Review
- Extracellular Vesicles in the Aging Male Reproductive System: Progresses and Perspectives.Advances in experimental medicine and biology · 2025Review
- Correlation between semen quality and the seminal biochemical markers: alpha-glucosidase, fructose, and zinc in infertile men compared with a normal population of men.Frontiers in endocrinology · 2025Article
- Do different male infertility factors impact embryological, cumulative pregnancy and neonatal outcomes in IVF/ICSI cycles? A retrospective cohort study.Human reproduction open · 2025Article
- Perspectives on biomarkers of reproductive aging for fertility and beyond.Nature aging · 2024Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This retrospective cohort study aimed to explore whether paternal age and semen quality parameters affect the embryological and clinical outcomes of ICSI with oocyte donation. A total of 339 oocyte donation (OD)-ICSI cycles were categorized into four groups according to the semen parameter profiles of the male counterparts: normozoospermia (NS, n = 184), oligozoospermia (OS, n = 41), asthenozoospermia (AS, n = 50), and oligoasthenozoospermia (OAS, n = 64). The effect of age, total sperm count, and progressive motility was separately analyzed for reproductive outcomes and compared between the study groups: fertilization, blastulation, and top-quality embryo rate, biochemical and clinical pregnancy, live birth, and miscarriage. A negative correlation between male age and fertilization rate was observed (r
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.