ReviewCEN case reports2022
New-onset pediatric nephrotic syndrome following Pfizer-BioNTech SARS-CoV-2 vaccination: a case report and literature review.
Review in CEN case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- Nephrotic syndrome following COVID-19 vaccination: a systematic review.Journal of nephrology · 2023Pooled it
- Acute and chronic kidney injury following COVID-19 infection and vaccination: a narrative review.European journal of translational myology · 2026Article
- Acute tubulointerstitial nephritis after the second dose of the Pfizer COVID-19 vaccine.Clinical and experimental vaccine research · 2025Article
- Association of COVID-19 vaccination with relapsed nephrotic syndrome and new onset nephrotic syndrome in children.Pediatric nephrology (Berlin, Germany) · 2025Article
- Two adolescents with frequently relapsing nephrotic syndrome newly diagnosed after SARS-CoV-2 vaccination: case report and literature review.CEN case reports · 2025Review
- Kidney complications associated with COVID-19 infection and vaccination in children and adolescents: a brief review.Clinical and experimental pediatrics · 2023Article
- Vaccines and nephrotic syndrome: efficacy and safety.Pediatric nephrology (Berlin, Germany) · 2023Review
- Immunogenicity and safety of SARS-CoV-2 mRNA vaccine in patients with nephrotic syndrome receiving immunosuppressive agents.Pediatric nephrology (Berlin, Germany) · 2023Article
- Two adolescent cases of acute tubulointerstitial nephritis after second dose of COVID-19 mRNA vaccine.Human vaccines & immunotherapeutics · 2022Article
- Renal Side Effects of COVID-19 Vaccination.Vaccines · 2022Review
- Intrinsic Kidney Pathology in Children and Adolescents Following COVID-19 Vaccination: A Systematic Review.Children (Basel, Switzerland) · 2022Review
- Minimal change disease and acute interstitial nephritis following SARS-CoV-2 BNT162b2 vaccination.Pediatric nephrology (Berlin, Germany) · 2022Article
- Minimal change disease and COVID-19 vaccination: Four cases and review of literature.Clinical nephrology. Case studies · 2022Article
- Renal Complications Following COVID-19 Vaccination: A Narrative Literature Review.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineReview
- The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease.Jornal brasileiro de nefrologiaArticle
- The COVID-19 pandemic in children and young people during 2020-2021: A complex discussion on vaccination.Journal of global healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various new vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been rapidly developed. The new onset and recurrence of nephrotic syndrome triggered by some vaccines have been documented and several adult cases of minimal change nephrotic syndrome newly developing after SARS-CoV-2 vaccination have been reported. However, no reports of pediatric cases have been published. Indications for SARS-CoV-2 vaccines have been expanded to those as young as 12 years old and vaccination of children has just started in Japan. We encountered a 15-year-old boy without underlying disease who newly developed nephrotic syndrome after SARS-CoV-2 vaccination with BNT162b2 (Pfizer-BioNTech). He developed eyelid edema 4 days after vaccination and peripheral edema of the lower extremities a further 4 days later. Twenty-one days after vaccination, 60 mg of oral daily prednisolone was started. He achieved complete remission in 12 days without complications such as hypertension or acute kidney injury. We clinicians should be aware of the possibility of nephrotic syndrome developing after SARS-CoV-2 vaccination, not only in adults, but also in children.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.