ArticleJournal of nephrology2022
Hypertension and cardiovascular risk factor management in a multi-ethnic cohort of adults with CKD: a cross sectional study in general practice.
Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Cardiovascular-kidney-metabolic syndrome: candidate subtypes and genetic risk factors.BMC medical genomics · 2026Article
- Factors Associated With Physiological Dysregulation Among US Adults Aged 45 Years and Older: A Nationally Representative Study.Journal of aging research · 2026Article
- Postpartum kidney disease associated with placental abruption: a population-based retrospective cohort study.Lancet regional health. Americas · 2025Article
- Outcomes for older people with screening-detected versus existing chronic kidney disease: a cohort study with data linkage.BJGP open · 2025Article
- The management of chronic kidney disease in primary care in Denmark: patient characteristics, treatment, follow-up, progression and referral.Clinical kidney journal · 2025Article
- Have People Treated With Antihypertensives Been Diagnosed With Hypertension? A Cross-Sectional Study in Stockholm, Sweden.Pharmacoepidemiology and drug safety · 2025Article
- Remnant cholesterol for diabetic kidney disease risk stratification in type 2 diabetes: a machine learning-based prevention tool.Frontiers in nutrition · 2025Article
- Obesity and Chronic Kidney Disease: The Dual Epidemic in Cardiovascular Health.European cardiology · 2025Review
- Patients with Chronic Kidney Disease: Background Factors Associated with Experienced Health Status and Life Satisfaction.Patient related outcome measures · 2024Article
- Prevalence and predictors of chronic kidney disease among type 2 diabetic patients worldwide, systematic review and meta-analysis.Diabetology & metabolic syndrome · 2023Review
- Projecting the Epidemiological and Economic Impact of Chronic Kidney Disease Using Patient-Level Microsimulation Modelling: Rationale and Methods of Inside CKD.Advances in therapy · 2023Article
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Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension, especially if poorly controlled, is a key determinant of chronic kidney disease (CKD) development and progression to end stage renal disease (ESRD).
aimTo assess hypertension and risk factor management, and determinants of systolic blood pressure control in individuals with CKD and hypertension. DESIGN AND
settingCross-sectional survey using primary care electronic health records from 47/49 general practice clinics in South London.
methodsKnown effective interventions, management of hypertension and cardiovascular disease (CVD) risk in patients with CKD Stages 3-5 were investigated. Multivariable logistic regression analysis examined the association of demographic factors, comorbidities, deprivation, and CKD coding, with systolic blood pressure control status as outcome. Individuals with diabetes were excluded.
resultsAdults with CKD Stages 3-5 and hypertension represented 4131/286,162 (1.4%) of the total population; 1984 (48%) of these individuals had undiagnosed CKD without a recorded CKD clinical code. Hypertension was undiagnosed in 25% of the total Lambeth population, and in patients with CKD without diagnosed hypertension, 23.0% had systolic blood pressure > 140 mmHg compared with 39.8% hypertensives, p < 0.001. Multivariable logistic regression revealed that factors associated with improved systolic blood pressure control in CKD included diastolic blood pressure control, serious mental illness, history of cardiovascular co-morbidities, CKD diagnostic coding, and age < 60 years. African ethnicity and obesity were associated with poorer systolic blood pressure control.
conclusionWe found both underdiagnosed CKD and underdiagnosed hypertension in patients with CKD. The poor systolic blood pressure control in older age groups ≥ 60 years and in Black African or obese individuals is clinically important as these groups are at increased risk of mortality for cardiovascular diseases.
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