Evidence map›Paper›PMID 34782859›Full record

ReviewMicrobial cell (Graz, Austria)2021

Lipid and fatty acid metabolism in trypanosomatids.

Giovana Parreira de Aquino, Marco Antonio Mendes Gomes, Roberto Köpke Salinas, Maria Fernanda Laranjeira-Silva

Abstract readReview
In one paragraph

Review in Microbial cell (Graz, Austria), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Pathogens (Basel, Switzerland) · 2026
    Article
  2. Transcriptomic response to different heme sources inMicrobial cell (Graz, Austria) · 2026
    Article
  3. Article
  4. Application of a Non-Targeted Metabolomics Study inInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Unveiling the hemolymphatic miRNome composition of the schistosomiasis vector snailCurrent research in parasitology & vector-borne diseases · 2025
    Article
  11. Article
  12. Article
  13. bioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. M-iScience · 2024
    Article
  16. The intersection of hostMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovana Parreira de AquinoDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Marco Antonio Mendes GomesDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
Roberto Köpke SalinasDepartment of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Maria Fernanda Laranjeira-SilvaDepartment of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trypanosomiases and leishmaniases are neglected tropical diseases that have been spreading to previously non-affected areas in recent years. Identification of new chemotherapeutics is needed as there are no vaccines and the currently available treatment options are highly toxic and often ineffective. The causative agents for these diseases are the protozoan parasites of the Trypanosomatidae family, and they alternate between invertebrate and vertebrate hosts during their life cycles. Hence, these parasites must be able to adapt to different environments and compete with their hosts for several essential compounds, such as amino acids, vitamins, ions, carbohydrates, and lipids. Among these nutrients, lipids and fatty acids (FAs) are essential for parasite survival. Trypanosomatids require massive amounts of FAs, and they can either synthesize FAs

Indexed as

chemotherapeuticselongaseshost-parasite interactionLeishmanianeglected tropical diseasesTrypanosoma bruceiTrypanosoma cruzi

Identifiers

PMID34782859
PMCPMC8561143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.