ArticleNature neuroscience2021
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence.
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Article in Nature neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
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Who cites it
40 citing papers in PubMed, 77 citations in OpenAlex.
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- Cellular and molecular mechanisms of astrocyte plasticity in learning and memory.Trends in neurosciences · 2026Review
- A Low-Parameter Adaptive Framework Based on Gaussian Mixture Modeling for Detecting Weak Astrocytic Calcium Signals in Two-Photon Imaging.Bioengineering (Basel, Switzerland) · 2026Article
- Astrocytes mediate the pro-cognitive value of α7nAChRs and of α7nAChR-targeting therapeutics.bioRxiv : the preprint server for biology · 2026Article
- Article
- Tonotopic organization in the basal region of the ventromedial nucleus of the thalamus revealed by fiber photometry recording.Neurophotonics · 2026Article
- Regular versus Irregular Exercise Differentially Modulates Hippocampal-Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Astrocytes as Active Participants in Memory.Journal of neurochemistry · 2025Review
- Article
- Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer's Disease Pathophysiology.Life (Basel, Switzerland) · 2025Review
- The Role of Astrocytes in Synaptic Dysfunction and Memory Deficits in Alzheimer's Disease.Biomolecules · 2025Review
- Nicotine Ameliorates α-Synuclein Preformed Fibril-Induced Behavioral Deficits and Pathological Features in Mice.Applied biochemistry and biotechnology · 2025Article
- Cholinergic signaling to CA1 astrocytes controls fear extinction.Science advances · 2025Article
- Astrocyte-to-neuron HNature metabolism · 2025Article
- Characterization of the Astrocyte Calcium Response to Norepinephrine in the Ventral Tegmental Area.Cells · 2024Article
- Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice.Nature communications · 2024Article
- Mapping multi-regional functional connectivity of astrocyte-neuronal networks during behaviors.Neurophotonics · 2024Article
- Modulation of cortical representations of sensory and contextual information underlies aversive associative learning.Cell reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 8 institutions in 3 countries.
Kuan Zhang *Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Rita Förster *Institute of Neuroscience, Technical University of Munich, Munich, Germany.
Wenjing HeBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Xiang LiaoCenter for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China.ORCID http://orcid.org/0000-0001-6324-5206
Jin LiBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Chuanyan YangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Han QinCenter for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China.
Meng WangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Ran DingBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Ruijie LiBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Tingliang JianBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Yanhong WangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Jianxiong ZhangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.ORCID http://orcid.org/0000-0003-2245-8752
Zhiqi YangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Wenjun JinBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Yonghai ZhangInstitute of Neuroscience, Technical University of Munich, Munich, Germany.
Song QinDepartment of Anatomy Histology and Embryology, Shanghai Medical College, Fudan University, Shanghai, China.
Yacheng LuDepartment of Anatomy Histology & Embryology, Air Force Medical University, Xi'an, China.
Tao ChenDepartment of Anatomy Histology & Embryology, Air Force Medical University, Xi'an, China.ORCID http://orcid.org/0000-0003-1956-0553
Jillian StobartInstitute of Pharmacology and Toxicology, University of Zurich and Neuroscience Center Zurich, Eidgenössische Technische Hochschule, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-7765-1408
Bruno WeberInstitute of Pharmacology and Toxicology, University of Zurich and Neuroscience Center Zurich, Eidgenössische Technische Hochschule, Zurich, Switzerland.
Helmuth AdelsbergerInstitute of Neuroscience, Technical University of Munich, Munich, Germany.
Arthur KonnerthInstitute of Neuroscience, Technical University of Munich, Munich, Germany. arthur.konnerth@tum.de.ORCID http://orcid.org/0000-0002-9548-2676
Xiaowei ChenBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China. xiaowei_chen@tmmu.edu.cn.ORCID http://orcid.org/0000-0003-0906-6666
Army Medical University · CNMunich Cluster for Systems Neurology · DEChongqing University · CNUniversity of Zurich · CHAir Force Medical University · CNGuangxi University · CNShanghai Medical College of Fudan University · CNXi'an Jiaotong University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Memory persistence is a fundamental cognitive process for guiding behaviors and is considered to rely mostly on neuronal and synaptic plasticity. Whether and how astrocytes contribute to memory persistence is largely unknown. Here, by using two-photon Ca
Indexed as
alpha7 Nicotinic Acetylcholine ReceptorAstrocytesFearAnimalsLearningMiceSynaptic Transmissionalpha7 Nicotinic Acetylcholine ReceptorChrna7 protein, mouse
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.