ArticleInternational journal of obesity (2005)2022
Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis.
Article in International journal of obesity (2005), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Association of Timing of Moderate-to-Vigorous Physical Activity With Changes in Glycemic Control Over 4 Years in Adults With Type 2 Diabetes From the Look AHEAD Trial.Diabetes care · 2023Trial
- The impact of physical activity and exercise timing on metabolic health among individuals at high risk of type 2 diabetes.Diabetologia · 2026Review
- Inflammatory, metabolic, and vascular pathways linking cardiorespiratory fitness to cognition: Results from the IGNITE study.Brain, behavior, & immunity - health · 2026Article
- Associations of Moderate-to-Vigorous Physical Activity Timing With Type 2 Diabetes Incidence in UK Biobank and Prevalent Glycemic Measures in NHANES.Diabetes care · 2026Article
- Associations between the timing of 24 h physical activity and diabetes mellitus: results from a nationally representative sample of the US population.Diabetologia · 2025Article
- Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).International journal of obesity (2005) · 2025Observational
- Longitudinal timing of physical activity and associated cardiometabolic and behavioral health outcomes in young adults.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Association between device-based measured physical activity timing and depression risk: a prospective cohort study of UK Biobank participants.BMJ public health · 2025Article
- Associations Between Physical Activity Patterns and Cardiovascular Events and Risk Factors: Cross-Sectional and Prospective Studies.JACC. Advances · 2024Article
- Diurnal timing of physical activity and risk of colorectal cancer in the UK Biobank.BMC medicine · 2024Article
- Article
- Association between circadian physical activity trajectories and incident type 2 diabetes in the UK Biobank.Scientific reports · 2024Article
- Deep learning of movement behavior profiles and their association with markers of cardiometabolic health.BMC medical informatics and decision making · 2024Article
- Effects of the Timing of Intense Physical Activity on Hypertension Risk in a General Population: A UK-Biobank Study.Current hypertension reports · 2024Review
- Machine learning in physical activity, sedentary, and sleep behavior research.Journal of activity, sedentary and sleep behaviors · 2024Review
- Physical Activity Pattern of Adults With Metabolic Syndrome Risk Factors: Time-Series Cluster Analysis.JMIR mHealth and uHealth · 2023Article
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about the impact of timing as opposed to frequency and intensity of daily physical activity on metabolic health. Therefore, we assessed the association between accelerometery-based daily timing of physical activity and measures of metabolic health in sedentary older people.
methodsHourly mean physical activity derived from wrist-worn accelerometers over a 6-day period was collected at baseline and after 3 months in sedentary participants from the Active and Healthy Ageing study. A principal component analysis (PCA) was performed to reduce the number of dimensions (e.g. define periods instead of separate hours) of hourly physical activity at baseline and change during follow-up. Cross-sectionally, a multivariable-adjusted linear regression analysis was used to associate the principal components, particularly correlated with increased physical activity in data-driven periods during the day, with body mass index (BMI), fasting glucose and insulin, HbA1c and the homeostatic model assessment for insulin resistance (HOMA-IR). For the longitudinal analyses, we calculated the hourly changes in physical activity and change in metabolic health after follow-up.
resultsWe included 207 individuals (61.4% male, mean age: 64.8 [SD 2.9], mean BMI: 28.9 [4.7]). Higher physical activity in the early morning was associated with lower fasting glucose (-2.22%, 95% CI: -4.19, -0.40), fasting insulin (-13.54%, 95%CI: -23.49, -4.39), and HOMA-IR (-16.07%, 95%CI: -27.63, -5.65). Higher physical activity in the late afternoon to evening was associated with lower BMI (-2.84%, 95% CI: -4.92, -0.70). Higher physical activity at night was associated with higher BMI (2.86%, 95% CI: 0.90, 4.78), fasting glucose (2.57%, 95% CI: 0.70, 4.30), and HbA1c (2.37%, 95% CI: 1.00, 3.82). Similar results were present in the prospective analysis.
conclusionSpecific physical activity timing patterns were associated with more beneficial metabolic health, suggesting particular time-dependent physical activity interventions might maximise health benefits.
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