Evidence map›Paper›PMID 34782605›Full record

ArticleNature communications2021

Finding positive meaning in memories of negative events adaptively updates memory.

Megan E Speer, Sandra Ibrahim, Daniela Schiller, Mauricio R Delgado

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 71 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Emotion regulation modulates subsequent control of unwanted memories.Social cognitive and affective neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Hooking the Self Onto the Past: How Positive Autobiographical Memory Retrieval Benefits People With Social Anxiety.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  13. Aversive memories can be weakened during human sleep via the reactivation of positive interfering memories.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. Individuals who see the good in the bad engage distinctive default network coordination during post-encoding rest.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Article
  19. Peer facilitation of emotion regulation in adolescence.Developmental cognitive neuroscience · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Megan E SpeerDepartment of Psychology, Columbia University, New York, NY, US. speer.meg.e@gmail.com.ORCID 0000-0002-5208-4133
Sandra IbrahimDepartment of Psychology, Rutgers University, Newark, NJ, US.
Daniela SchillerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, US.ORCID 0000-0002-0357-7724
Mauricio R DelgadoDepartment of Psychology, Rutgers University, Newark, NJ, US. delgado@psychology.rutgers.edu.ORCID 0000-0002-5686-0507
Rutgers, The State University of New Jersey · USAllen Institute for Brain Science · USColumbia University · US

Funding

Neural mechanisms of avoidance learning and active coping via emotion regulationR01DA027764 · NIDA · RUTGERS THE STATE UNIV OF NJ NEWARK · PI DELGADO, MAURICIO R. · 2009 to 2016
$2.2M
NIDA NIH HHS R01 DA027764
6 · The paper itself

Abstract

Finding positive meaning in past negative memories is associated with enhanced mental health. Yet it remains unclear whether it leads to updates in the memory representation itself. Since memory can be labile after retrieval, this leaves the potential for modification whenever its reactivated. Across four experiments, we show that positively reinterpreting negative memories adaptively updates them, leading to the re-emergence of positivity at future retrieval. Focusing on the positive aspects after negative recall leads to enhanced positive emotion and changes in memory content during recollection one week later, remaining even after two months. Consistent with a reactivation-induced reconsolidation account, memory updating occurs only after a reminder and twenty four hours, but not a one hour delay. Multi-session fMRI showed adaptive updates are reflected in greater hippocampal and ventral striatal pattern dissimilarity across retrievals. This research highlights the mechanisms by which updating of maladaptive memories occurs through a positive emotion-focused strategy.

Indexed as

AdolescentAdultBehaviorCognitionCognitive NeuroscienceFemaleHippocampusHumansMaleMemoryMental RecallYoung Adult

Identifiers

PMID34782605
PMCPMC8593143
OpenAlexW3212341554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.