Evidence map›Paper›PMID 34782479›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Jessica E Schwarz, Anna N King, Cynthia T Hsu, Annika F Barber, Amita Sehgal

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  13. The NFκBbioRxiv : the preprint server for biology · 2023
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica E SchwarzHHMI, University of Pennsylvania, Philadelphia, PA 19104.
Anna N KingHHMI, University of Pennsylvania, Philadelphia, PA 19104.
Cynthia T HsuHHMI, University of Pennsylvania, Philadelphia, PA 19104.
Annika F BarberHHMI, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-5058-939X
Amita SehgalHHMI, University of Pennsylvania, Philadelphia, PA 19104; amita@pennmedicine.upenn.edu.ORCID 0000-0001-7354-9641
University of Pennsylvania · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Training in Alzheimer’s and Age-Related Neurodegenerative DiseasesT32AG000255 · NIA · UNIVERSITY OF PENNSYLVANIA · PI ALICE S CHEN-PLOTKIN, VIRGINIA M LEE · 1997 to 2026
$12.5M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008216 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI EPSTEIN, DOUGLAS J · 1987 to 2023
$8.3M
Graduate Training in NeuroscienceT32NS105607 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Marc V Fuccillo, Minghong Ma · 2018 to 2026
$5.4M
Interaction between circadian and sleep circuitsR01NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI AMITA SEHGAL · 2005 to 2026
$4.8M
Cycling in a circadian circuitR37NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA · 2015 to 2021
$2.7M
Integration of circadian and homeostatic signals in a peptidergic circuit in DrosophilaR00NS105942 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI BARBER, ANNIKA FITZPATRICK · 2020 to 2022
$856k
Cycling of circadium rhythm proteinsR56NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA · 2010 to 2010
$400k
Integration of circadian and homeostatic signals in a peptidergic circuit in DrosophilaK99NS105942 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BARBER, ANNIKA FITZPATRICK · 2018 to 2019
$163k
Neural mechanisms underlying circadian rhythms in behaviorF31NS100395 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KING, ANNA · 2017 to 2018
$70k
NIA NIH HHS T32 AG000255NIGMS NIH HHS T32 GM008216NIH HHS P40 OD018537NINDS NIH HHS F31 NS100395NINDS NIH HHS K99 NS105942NINDS NIH HHS R00 NS105942NINDS NIH HHS R01 NS048471NINDS NIH HHS R37 NS048471NINDS NIH HHS R56 NS048471NINDS NIH HHS T32 NS105607
6 · The paper itself

Abstract

Sleep is controlled by homeostatic mechanisms, which drive sleep after wakefulness, and a circadian clock, which confers the 24-h rhythm of sleep. These processes interact with each other to control the timing of sleep in a daily cycle as well as following sleep deprivation. However, the mechanisms by which they interact are poorly understood. We show here that

Indexed as

AnimalsCircadian ClocksDrosophila melanogasterDrosophila ProteinsFemaleHomeostasisLocomotionMutationNeuronsNeuropeptidesSleepSleep DeprivationWakefulnessDrosophila ProteinsHug protein, DrosophilaNeuropeptidescircadian rhythmscircuitDrosophilaneuropeptidessleep homeostasis

Identifiers

PMID34782479
PMCPMC8617458
OpenAlexW3214620518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.