Evidence map›Paper›PMID 34782462›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Dynamic competition between a ligand and transcription factor NusA governs riboswitch-mediated transcription regulation.

Adrien Chauvier, Pujan Ajmera, Rajeev Yadav, Nils G Walter

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. RfaH licenses RNA polymerase for long-range transcription.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Localized ribosome access and distal tuning via thebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
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  8. Review
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  10. Review
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  14. Divergent molecular assembly and catalytic mechanisms between bacterial and archaeal RNase P in pre-tRNA cleavage.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Review
  17. Review
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  19. Article
  20. RNA folding kinetics control riboswitch sensitivity in vivo.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adrien ChauvierSingle Molecule Analysis Group, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0003-4473-6194
Pujan AjmeraSingle Molecule Analysis Group, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0001-9509-6807
Rajeev YadavSingle Molecule Analysis Group, University of Michigan, Ann Arbor, MI 48109.ORCID 0000-0002-9652-3388
Nils G WalterSingle Molecule Analysis Group, University of Michigan, Ann Arbor, MI 48109; nwalter@umich.edu.ORCID 0000-0002-7301-1275
University of Michigan · US

Funding

The RNA nanomachines of the gene expression machinery dissected at the single molecule levelR35GM131922 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NILS G WALTER · 2019 to 2026
$6.9M
U-turn of the Hepatitis Delta Virus RibozymeR01GM062357 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WALTER, NILS G · 2001 to 2019
$5.8M
Cotranscriptional folding of single riboswitchesR01GM118524 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WALTER, NILS G · 2016 to 2018
$911k
NIGMS NIH HHS R01 GM062357NIGMS NIH HHS R01 GM118524NIGMS NIH HHS R35 GM131922
6 · The paper itself

Abstract

Cotranscriptional RNA folding is widely assumed to influence the timely control of gene expression, but our understanding remains limited. In bacteria, the fluoride (F

Indexed as

LigandsRiboswitchDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialRNA, BacterialRNA FoldingTranscriptional Elongation FactorsTranscription FactorsTranscription, GeneticDNA-Directed RNA PolymerasesEscherichia coli ProteinsLigandsnusA protein, E coliRiboswitchRNA, BacterialTranscriptional Elongation FactorsTranscription Factorscotranscriptional foldingNusAriboswitchRNA polymerase pausingsingle-molecule fluorescence microscopy

Identifiers

PMID34782462
PMCPMC8617461
OpenAlexW3207705237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.