Evidence map›Paper›PMID 34782327›Full record

ArticleBMJ open respiratory research2021

Assistive technologies for home NIV in patients with COPD: feasibility and positive experience with remote-monitoring and volume-assured auto-EPAP NIV mode.

Grace McDowell, Maksymilian Sumowski, Hannah Toellner, Sophia Karok, Ciara O'Dwyer, James Hornsby, David J Lowe, Christopher M Carlin

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Grace McDowellRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Maksymilian SumowskiRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Hannah ToellnerRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Sophia KarokResMed Data Solutions, ResMed Science Centre, Dublin, Ireland.
Ciara O'DwyerResMed Data Solutions, ResMed Science Centre, Dublin, Ireland.
James HornsbyRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
David J LoweRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Christopher M CarlinRespiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK christopher.carlin@ggc.scot.nhs.uk.
Queen Elizabeth University Hospital · GBResMed (Netherlands) · NLRespiratory Clinical Trials · AUTa Solutions (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcomes for patients with chronic obstructive pulmonary disease (COPD) with persistent hypercapnic respiratory failure are improved by long-term home non-invasive ventilation (NIV). Provision of home-NIV presents clinical and service challenges. The aim of this study was to evaluate outcomes of home-NIV in hypercapnic patients with COPD who had been set-up at our centre using remote-monitoring and iVAPS-autoEPAP NIV mode (Lumis device, ResMed).

methodsRetrospective analysis of a data set of 46 patients with COPD who commenced remote-monitored home-NIV (AirView, ResMed) between February 2017 and January 2018. Events including time to readmission or death at 12 months were compared with a retrospectively identified cohort of 27 patients with hypercapnic COPD who had not been referred for consideration of home-NIV.

resultsThe median time to readmission or death was significantly prolonged in patients who commenced home-NIV (median 160 days, 95% CI 69.38 to 250.63) versus the comparison cohort (66 days, 95% CI 21.9 to 110.1; p<0.01). Average time to hospital readmission was 221 days (95% CI, 47.77 to 394.23) and 70 days (95% CI, 55.31 to 84.69; p<0.05), respectively. Median decrease in bicarbonate level of 4.9 mmol/L (p<0.0151) and daytime partial pressure of carbon dioxide 2.2 kPa (p<0.032) in home-NIV patients with no required increase in nurse home visits is compatible with effectiveness of this service model. Median reduction of 14 occupied bed days per annum was observed per patient who continued home-NIV throughout the study period (N=32).

conclusionThese findings demonstrate the feasibility and provide initial utility data for a technology-assisted service model for the provision of home-NIV therapy for patients with COPD.

Indexed as

Noninvasive VentilationPulmonary Disease, Chronic ObstructiveSelf-Help DevicesFeasibility StudiesHumansRetrospective StudiesCOPD exacerbationsnon invasive ventilation

Identifiers

PMID34782327
PMCPMC8593724
OpenAlexW3213114566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.