Evidence map›Paper›PMID 34782023›Full record

ArticleArchives of public health = Archives belges de sante publique2021

Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study.

Trésor Bayebila Menanzambi, Patrice Dufour, Catherine Pirard, Jean Nsangu, Jean-Pierre Mufusama, Jérémie Mbinze Kindenge, Roland Marini Djang'eing'a, Corinne Charlier

Open access · goldAbstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Trésor Bayebila MenanzambiFaculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo. baytresor_pharma@yahoo.fr.ORCID http://orcid.org/0000-0002-2734-3148
Patrice DufourLaboratory of Clinical, Forensic and Environmental Toxicology, University of Liege (ULiege), CHU (B35), 4000, Liege, Belgium.
Catherine PirardLaboratory of Clinical, Forensic and Environmental Toxicology, University of Liege (ULiege), CHU (B35), 4000, Liege, Belgium.
Jean NsanguFaculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean-Pierre MufusamaFaculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jérémie Mbinze KindengeFaculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Roland Marini Djang'eing'aCenter for Interdisciplinary Research on Medicines (C.I.R.M), University of Liege (ULiege), CHU (B35), 4000, Liege, Belgium.
Corinne CharlierLaboratory of Clinical, Forensic and Environmental Toxicology, University of Liege (ULiege), CHU (B35), 4000, Liege, Belgium.
University of Kinshasa · CDUniversity of Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnvironmental pollutants are known to be ubiquitous and may present toxic effects (endocrine-disruption properties, carcinogenicity …) and represent a real threat to human health. The aim of the present pilot study was to assess the content of environmental pollutants (inorganic, persistent, and non-persistent pollutants) in biological samples (urine, serum, and whole blood), collected from volunteers in Kinshasa, capital of Democratic Republic of Congo, in order to identify pollutants of interest and to design a protocol for a larger scale study.

methodsFrom randomly selected 15 volunteers living in Kinshasa, aged from 25 to 66 years, (mean age = 43.4 years), including 10 men and 5 women, urine, whole blood, and serum samples were used in this study to estimate the contents in these environmental pollutants, using inductively coupled plasma mass spectrometry, gas chromatography coupled to mass spectrometry, and liquid chromatography coupled to mass spectrometry.

resultsWhen compared to data nationally and internationally available, the preliminary outcomes of this study indicated a very high level of exposure to environmental pollutants in the population of Kinshasa, especially for heavy metals, parabens and triclosan. To a lesser extent, contamination measured for glyphosate, phthalates, organochlorine pesticides, pyrethroids and dialkylphosphate pesticides was also significant. In contrast, the investigated population of Kinshasa was found to be weakly exposed to other persistent organic pollutants like polychlorinated biphenyls, brominated flame retardants, phenolic organohalogens, and perfluoroalkyl substances.

conclusionAlthough the biologic fluids were collected from a limited number of volunteers (n = 15), the results of the present report clearly indicate that the population of Kinshasa is not spared by the investigated environmental pollutants. Moreover, this study gives us important information to design a larger scale study protocol.

Indexed as

Bio-surveillanceEnvironmental pollutantsKinshasaSerumSmall pilot studyUrineWhole blood

Identifiers

PMID34782023
PMCPMC8591802
OpenAlexW3139428902

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.