Evidence map›Paper›PMID 34781978›Full record

ArticleHealth and quality of life outcomes2021

Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients.

Titi Sahidah Fitriana, Fredrick Dermawan Purba, Rina Rahmatika, Riski Muhaimin, Nur Melani Sari, Gouke Bonsel, Elly Stolk, Jan J V Busschbach

Abstract read
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Psychometric properties comparison of EQ-5D-Y-3L and CHU-9D in children with adenoid hypertrophy.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
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  6. Valuation of the EQ-5D-Y-5L Using DCE Methods That Account for Nonlinear Time Preferences.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Article
  7. Article
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  9. Comparing the measurement properties of the EQ-5D-Y-3L, EQ-5D-Y-5L and CHU9D in children and adolescents: a measurement property study.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  10. Article
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  12. Validity and responsiveness of EQ-5D-Y in children with haematological malignancies and their caregivers.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Article
  13. Validation of the EQ-5D-Y-5L parent-proxy version among children with juvenile idiopathic arthritis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
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  20. Research progress on mechanism of follicle injury after ovarian tissue transplantation and protective strategies.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Titi Sahidah FitrianaDepartment of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus MC University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands. t.fitriana@erasmusmc.nl.ORCID http://orcid.org/0000-0001-5062-6886
Fredrick Dermawan PurbaDepartment of Developmental Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, Indonesia.
Rina RahmatikaFaculty of Psychology, YARSI University, Jakarta, Indonesia.
Riski MuhaiminDepartment of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Nur Melani SariDepartment of Child Health, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
Gouke BonselThe EuroQol Research Foundation, Rotterdam, The Netherlands.
Elly StolkThe EuroQol Research Foundation, Rotterdam, The Netherlands.
Jan J V BusschbachDepartment of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus MC University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.

Funding

EuroQol Research Foundation 20180140
6 · The paper itself

Abstract

backgroundThe adult versions EQ-5D-3L and EQ-5D-5L have been extensive compared. This is not the case for the EQ-5D youth versions. The study aim was to compare the measurement properties and responsiveness of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients.

methodsA sample of patients 8-16 years old with different diseases and a wide range of disease severity was asked to complete EQ-5D-Y-3L, EQ-5D-Y-5L, PedsQL Generic Core Scale, and selected, appropriate disease-specific instruments, three times. EQ-5D-Y-3L and EQ-5D-Y-5L were compared in terms of: feasibility, (re-)distribution properties, discriminatory power, convergent validity, test-retest reliability, and responsiveness.

results286 participating patients suffered from one of the following diseases: major beta-thalassemia, haemophilia, acute lymphoblastic leukaemia, acute illness. Missing responses were comparable between versions of the EQ-5D-Y, suggesting comparable feasibility. The number of patients in the best health state (level profile 11111) was equal in both EQ-5D-Y versions. The projection of EQ-5D-Y-3L scores onto EQ-5D-Y-5L for all dimensions showed that the two additional levels in EQ-5D-Y-5L slightly improved the accuracy of patients in reporting their problems, especially if severe. Convergent validity with PedsQL and disease-specific measures showed that the two EQ-5D-Y versions performed about equally. Test-retest reliability (EQ-5D-Y-3L 0.78 vs EQ-5D-Y-5L 0.84), and sensitivity for detecting health changes, were both better in EQ-5D-Y-5L.

conclusionsExtending the number of levels did not give clear superiority to EQ-5D-Y-5L over EQ-5D-Y-3L based on the criteria assessed in this study. However, increasing the number of levels benefitted EQ-5D-Y performance in the measurement of moderate to severe problems and especially in longitudinal study designs.

Indexed as

Quality of LifeAdolescentAdultChildHumansLongitudinal StudiesPsychometricsReproducibility of ResultsSurveys and QuestionnairesEQ-5D-Y-3L paediatric patientsEQ-5D-Y-5LHealth-related quality of lifePsychometrics

Identifiers

PMID34781978
PMCPMC8591892

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.