ArticleEnvironmental health : a global access science source2021
Joint effect of 25-hydroxyvitamin D and secondhand smoke exposure on hypertension in non-smoking women of childbearing age: NHANES 2007-2014.
Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Passive smoking and the risk of hypertension in nonsmoking adults: a systematic review and meta-analysis.PeerJ · 2026Pooled it
- Pooled it
- The joint effect of vitamin-D status and tobacco exposure on overweight and obesity in children.The British journal of nutrition · 2024Article
- Association between dietary inflammatory index and all-cause mortality in patients with osteopenia or osteoporosis: A retrospective cohort study from the NHANES 2007-2018.Preventive medicine reports · 2024Article
- Association between dietary carotenoid intakes and the risk of asthma in children and adolescents: evidence from the National Health and Nutrition Examination Survey 2007-2016.Translational pediatrics · 2024Article
- Potential interaction of sugar intake and tobacco exposure on dental caries in adults-A cross-sectional study from the National Health and Nutrition Examination Survey.Journal of dental sciences · 2024Article
- Article
- Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hypertension in American adults: a NHANES cross-sectional study.Frontiers in physiology · 2024Article
- Inverse association between serum iron levels and Hashimoto's thyroiditis in United States females of reproductive age: analysis of the NHANES 2007-2012.Frontiers in nutrition · 2024Article
- Association between dietary fiber intake and all-cause and CVD-caused mortality among heart failure survivors: a cohort study from the NHANES database.Frontiers in cardiovascular medicine · 2024Article
- Adherence to the Mediterranean diet regulates the association between osteopenia and the risk of all-cause mortality in general population.Journal of health, population, and nutrition · 2023Article
- Association of remnant cholesterol with hypertension, type 2 diabetes, and their coexistence: the mediating role of inflammation-related indicators.Lipids in health and disease · 2023Article
- The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United States.Frontiers in nutrition · 2023Article
- Synergistic effects of overweight/obesity and high hemoglobin A1c status on elevated high-sensitivity C-reactive protein in Chinese adults: a cross-sectional study.Frontiers in nutrition · 2023Article
- Joint effect of overweight/obesity and tobacco exposure on hypertension in children aged 6-17 years: a cross-sectional study.Frontiers in pediatrics · 2023Article
- Comparison of Vitamin D Levels and Related Factors in Pregnant Women and Neonates Exposed to Second-Hand Smoke.Cureus · 2022Article
- Association of Serum 25(OH)D with Metabolic Syndrome in Chinese Women of Childbearing Age.Nutrients · 2022Article
- Association between soluble transferrin receptor and systolic hypertension in adults: National Health and Nutrition Examination Survey (2007-2010 and 2015-2018).Frontiers in cardiovascular medicine · 2022Article
- Association between Sensitivity to Thyroid Hormone Indices and Bone Mineral Density in US Males.International journal of endocrinology · 2022Article
- Association between organophosphate insecticide metabolites and lung function in U.S. adults: NHANES 2011-2012.Therapeutic advances in respiratory diseaseArticle
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundVitamin D deficiency (VDD) may increase the risk of hypertension in women of childbearing age, who may be exposed to secondhand smoke (SHS) simultaneously. Till now, few studies have investigated the joint effects of VDD and SHS on hypertension in this population. We evaluated whether exposure to SHS modified the association between VDD and hypertension.
methodsData from National Health and Nutrition Examination Surveys (NHANES) 2007-2014 were analyzed. Our research subjects were 2826 nonsmoking and nonpregnant women of childbearing age (20-44 years old). Hypertension was defined based either on systolic blood pressure (SBP) ≥ 130 mmHg and/or diastolic blood pressure (DBP) ≥ 80 mmHg or on now taking prescribed medicine for hypertension. The directed acyclic graphs (DAG) and the back-door criterion were used to select a minimal sufficient adjustment set of variables (MSAs) that would identify the unconfounded effect of 25(OH)D and hypertension. The interactive effect of VDD and SHS on hypertension was evaluated by using logistic regression models, followed by strata-specific analyses.
resultsThe prevalence of VDD in the hypertension group was significantly higher than that in the non-hypertension group (48.2% vs 41.0%, P = 0.008), as well as the exposure rate of SHS (39.1% vs 33.8%, P = 0.017). VDD was independently associated with nearly 50% increased risk of hypertension [adjusted odds ratio (aOR) = 1.43, 95% confidence interval (CI): 1.01, 2.04], while no significant association was observed between SHS and hypertension. However, SHS showed a significant synergistic effect on VDD with a higher aOR of 1.79 (95% CI: 1.14, 2.80) (P
conclusionThere exist synergistic effects of SHS and VDD on the prevalence of hypertension in American women of childbearing age, with more significant effects in women who were overweight or Non-Hispanic Black. Further studies are warranted to verify this finding in other populations, and the molecular mechanisms underlying the joint effect of SHS and VDD need to be elucidated.
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