Evidence map›Paper›PMID 34781731›Full record

ArticlemBio2021

A Fungal Transcription Regulator of Vacuolar Function Modulates Candida albicans Interactions with Host Epithelial Cells.

Philipp Reuter-Weissenberger, Juliane Meir, J Christian Pérez

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Microbiota and cancer: Elucidating the role ofWorld journal of clinical oncology · 2025
    Review
  4. Article
  5. Future microbiology · 2024
    Article
  6. A Putative Role ofMicroorganisms · 2023
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Philipp Reuter-WeissenbergerInterdisciplinary Center for Clinical Research, University Hospital Würzburg, Würzburg, Germany.
Juliane MeirInterdisciplinary Center for Clinical Research, University Hospital Würzburg, Würzburg, Germany.
J Christian PérezDepartment of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0001-5790-1481
Universitätsklinikum Würzburg · DEThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms typically maintain cellular homeostasis despite facing large fluctuations in their surroundings. Microbes that reside on human mucosal surfaces may experience significant variations in nutrient and ion availability as well as pH. Whether the mechanisms employed by these microbial cells to sustain homeostasis directly impact on the interplay with the host's mucosae remains unclear. Here, we report that the previously uncharacterized transcription regulator

Indexed as

AnimalsCandida albicansCandidiasisEpithelial CellsFemaleFungal ProteinsGene Expression Regulation, FungalHumansMiceMice, Inbred C57BLSpores, FungalTranscription FactorsVacuolesFungal ProteinsTranscription FactorsCandida albicanshost-pathogen interactionstranscriptional regulationvacuole

Identifiers

PMID34781731
PMCPMC8593675
OpenAlexW3214179518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.