Evidence map›Paper›PMID 34781645›Full record

ArticleKidney research and clinical practice2021

Metabolic risks in living kidney donors in South Korea.

Eunjeong Kang, Jina Park, Hyo Jeong Kim, Sehoon Park, Minsu Park, Yaerim Kim, Kwangsoo Kim, Sang Min Park, Dong-Wan Chae, Ho Jun Chin and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Kidney research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 1 country.

Eunjeong KangDepartment of Internal Medicine, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Jina ParkDepartment of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.
Hyo Jeong KimDivision of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea.
Sehoon ParkDepartment of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.
Minsu ParkDepartment of Statistics, Keimyung University, Daegu, Republic of Korea.
Yaerim KimDepartment of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Republic of Korea.
Kwangsoo KimTransdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Republic of Korea.
Sang Min ParkDepartment of Family Medicine, Seoul National University Hospital, Republic of Korea.
Dong-Wan ChaeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ho Jun ChinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Jung Pyo LeeDepartment of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
Sik LeeDepartment of Internal Medicine, Chonbuk National University Hospital, Jeonju, Republic of Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
Jang-Hee ChoDepartment of Internal Medicine, Kyungpook National University, Daegu, Republic of Korea.
Miyeun HanDepartment of Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Republic of Korea.
Yong Chul KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yon Su KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Insun ChoiDivision of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea.
Hajeong LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Seoul National University Hospital · KRNational Evidenc- based healthcare Collaborating Agency · KRSeoul National University · KRSeoul National University Bundang Hospital · KRChonnam National University Hospital · KREwha Womans University · KRHallym University · KRJeonbuk National University Hospital · KRKeimyung University · KRKorea University · KRKyungpook National University · KRSNUH SMG-SNU Boramae Medical Center · KR

Funding

National Evidence Collaborating Agency NECA-A-20-005
6 · The paper itself

Abstract

backgroundConsidering the growing prevalence of Western lifestyles and related chronic diseases occurring in South Korea, this study aimed to explore the progression of metabolic risk factors in living kidney donors.

methodsThis study enrolled living kidney donors from seven hospitals from 1982 to 2016. The controls were individuals that voluntarily received health check-ups from 1995 to 2016 that were matched with donors according to age, sex, diabetes status, baseline estimated glomerular filtration rate, and date of the medical record. Data on hyperuricemia, hypertension, hypercholesterolemia, and overweight/obesity were collected to determine metabolic risks. Logistic regressions with interaction terms between the medical record date and donor status were used to compare the trends in metabolic risks over time in the two groups.

resultsA total of 2,018 living kidney donors and matched non-donors were included. The median age was 44.0 years and 54.0% were women. The living kidney donors showed a lower absolute prevalence for all metabolic risk factors, except for those that were overweight/obese, than the non-donors. The proportion of subjects that were overweight/obese was consistently higher over time in the donor group. The changes over time in the prevalence of each metabolic risk were not significantly different between groups, except for a lower prevalence of metabolic risk factors ≥ 3 in donors.

conclusionOver time, metabolic risks in living kidney donors are generally the same as in non-donors, except for a lower prevalence of metabolic risk factors ≥3 in donors.

Indexed as

HypercholesterolemiaHyperuricemiaKidney transplantationLiving donorsRisk factors

Identifiers

PMID34781645
PMCPMC8685357
OpenAlexW3206654818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.