ArticleClinical endoscopy2021
Current Status of Endoscopic Vacuum Therapy in the Management of Esophageal Perforations and Post-Operative Leaks.
Article in Clinical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Endoscopic negative-pressure therapy for anastomotic leaks after upper gastrointestinal surgery: systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- VacStent as a novel therapeutic approach for esophageal perforations and anastomotic leaks- a systematic review of the literature.BMC surgery · 2025Pooled it
- EVT-Inspired Simplified Negative-Pressure Nasoesophageal Drainage for Cervical Abscess Secondary to Esophageal Perforation.The American journal of case reports · 2026Article
- Fatal cerebral gas embolism during endoluminal vacuum therapy for esophageal leak.Clinical journal of gastroenterology · 2026Article
- Real-world management and in-hospital outcomes of foreign body-associated esophageal perforations in the United States: a national retrospective cohort study.Clinical endoscopy · 2026Article
- T-tube insertion as a salvage procedure for failed primary repair in penetrating esophageal injury complicated by sepsis: a case report from low resource setting.International journal of surgery case reports · 2026Article
- Endoscopic Management of Post-Bariatric Surgery Complications: Diagnostic Work-Up and Innovative Approaches for Leak, Fistula, and Stricture Management.Diagnostics (Basel, Switzerland) · 2026Review
- Modified Negative Pressure Wound Therapy Using Surgical Drain and Occlusive Sutures for Leakage After Esophageal Injury.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Endoscopic vacuum therapy for gastrointestinal transmural defects: clinical outcomes and treatment implications: a retrospective study from Korea.Ewha medical journal · 2026Article
- Endoscopic management for gastrointestinal leaks, perforations, and fistulae: Technical tips and outcomes.World journal of gastrointestinal endoscopy · 2025Review
- Management of Gastric Fistulas After Gastric Sleeve Using E-VAC Therapy.Diagnostics (Basel, Switzerland) · 2025Article
- Treatment of Boerhaave syndrome: experience from a tertiary center.Surgical endoscopy · 2025Observational
- Endoscopic vacuum therapy for gastrointestinal transmural defects: a literature review.Clinical endoscopy · 2025Review
- A novel detachable over-the-scope clip system for the management of esophageal inlet perforation secondary to endoscopic ultrasonography procedures.Gastroenterology report · 2025Article
- Efficacy of endoscopic vacuum therapy in esophageal luminal defects: a systematic review and meta-analysis.Clinical endoscopy · 2025Article
- Prevention, detection and management of adverse events of third-space endoscopy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Management of an Aortoesophageal Fistula With Esophageal Endoluminal Wound Vacuum Therapy.Annals of thoracic surgery short reports · 2024Article
- VAC-Stent in the Treatment of Post-Esophagectomy Anastomotic Leaks: A New "Kid on the Block" Who Marries the Best of Old Techniques-A Review.Journal of clinical medicine · 2024Review
- Successful Endoscopic Vacuum-Assisted Closure Therapy for Esophageal Perforation: A Case Report.The Korean journal of helicobacter and upper gastrointestinal research · 2024Article
- Choosing the best endoscopic approach for post-bariatric surgical leaks and fistulas: Basic principles and recommendations.World journal of gastroenterology · 2023Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal wall defects, including perforations and postoperative leaks, are associated with high morbidity and mortality and pose a significant management challenge. In light of the high morbidity of surgical management or revision, in recent years, endoscopic vacuum therapy (EVT) has emerged as a novel alternative treatment strategy. EVT involves transoral endoscopic placement of a polyurethane sponge connected to an externalized nasogastric tube to provide continuous negative pressure with the intention of promoting defect healing, facilitating cavity drainage, and ameliorating sepsis. In the last decade, EVT has become increasingly adopted in the management of a diverse spectrum of esophageal defects. Its popularity has been attributed in part to the growing body of evidence suggesting superior outcomes and defect closure rates in excess of 80%. This growing body of evidence, coupled with the ongoing evolution of the technology and techniques of deployment, suggests that the utilization of EVT has become increasingly widespread. Here, we aimed to review the current status of the field, addressing the mechanism of action, indications, technique methodology, efficacy, safety, and practical considerations of EVT implementation. We also sought to highlight future directions for the use of EVT in esophageal wall defects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.