Evidence map›Paper›PMID 34781261›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Case Report: Dengue Hemorrhagic Fever with Ischemic Stroke.

Basnayake Wasala Mudiyanselage Kumarini Eranthika Basnayake, Kaluachchi Gamage Samanthi Kumari Somaratne, Chathuri Udeshika Goonetilleke, Pattiniya Markkala Yasoma Indrani Tilakaratna, Udaya Kumara Ranawaka

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In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. [Ischemic stroke in dengue: Are we facing an immunomediated response? A case report]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2026
    Article
  4. Case Report and Review of the Literature: Ischemic Stroke in Dengue Virus Infection.The American journal of tropical medicine and hygiene · 2024
    Review
  5. Article
  6. Ischemic Stroke During Dengue Infection: A Report of 2 Cases.The American journal of case reports · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Basnayake Wasala Mudiyanselage Kumarini Eranthika BasnayakeColombo North Teaching Hospital, Ragama, Sri Lanka.
Kaluachchi Gamage Samanthi Kumari SomaratneColombo North Teaching Hospital, Ragama, Sri Lanka.
Chathuri Udeshika GoonetillekeColombo North Teaching Hospital, Ragama, Sri Lanka.
Pattiniya Markkala Yasoma Indrani TilakaratnaFaculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Udaya Kumara RanawakaFaculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Colombo North Teaching Hospital · LKUniversity of Kelaniya · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several neurological manifestations are recognized in dengue infection, but stroke is a rare complication. We report a case of ischemic stroke in a patient with dengue hemorrhagic fever. A 52-year-old previously healthy male presented with a history of fever for 2 days, and left-sided weakness and numbness of sudden onset. MRI scanning showed a right-sided thalamic lacunar infarct. Diagnosis of dengue fever was made based on leuco-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and positive dengue IgM antibodies. Severity of limb weakness correlated with the critical phase of dengue hemorrhagic fever (DHF). He was discharged home with good recovery from neurological symptoms and disability. Strokes are rare in dengue, and are mainly hemorrhagic strokes related to thrombocytopenia. Ischemic stroke is even rarer. More evidence is needed for confirmation of dengue as a pathogenic mechanism of ischemic stroke.

Indexed as

BrainDengueFeverHumansIschemic StrokeMagnetic Resonance ImagingMaleMiddle AgedMuscle WeaknessSevere DengueTertiary Care CentersThrombocytopeniaTomography, X-Ray Computed

Identifiers

PMID34781261
PMCPMC8832929
OpenAlexW3213472310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.