Evidence map›Paper›PMID 34781241›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2021

Acute bronchiolitis and respiratory syncytial virus seasonal transmission during the COVID-19 pandemic in Spain: A national perspective from the pediatric Spanish Society (AEP).

David Torres-Fernandez, Aina Casellas, Maria José Mellado, Cristina Calvo, Quique Bassat

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  5. Respiratory virus circulation during pandemic: Why were some viruses still circulating?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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  9. Seasonality of the incidence of bronchiolitis in infants - Brazil, 2016-2022: An interrupted time-series analysis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024
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  19. Respiratory Syncytial Virus Pediatric Hospitalization in the COVID-19 Era.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

David Torres-FernandezISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain. Electronic address: david.torres@isglobal.org.
Aina CasellasISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Maria José MelladoPediatric Infectious Diseases Unit, Pediatrics Department, University Hospital La Paz, Madrid (Spain). Fundación IdiPaz. Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain; Asociación Española de Pediatría (AEP), Spain.
Cristina CalvoPediatric Infectious Diseases Unit, Pediatrics Department, University Hospital La Paz, Madrid (Spain). Fundación IdiPaz. Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain; Asociación Española de Pediatría (AEP), Spain.
Quique BassatISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique; ICREA, Pg. Lluís Companys 23, 08010 Barcelona, Spain; Pediatrics Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Barcelona, Spain; Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Asociación Española de Pediatría (AEP), Spain. Electronic address: quique.bassat@isglobal.org.
Universitat de Barcelona · ESAsociación Española de Urología · ESHospital La Paz Institute for Health Research · ESHospital Sant Joan de Déu Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectivesThe COVID-19 pandemic and the widespread associated use of non-pharmaceutical interventions have impacted viral circulation and the incidence of respiratory tract infections. We compared Pediatric Emergency Department visits, bronchiolitis admissions, and respiratory syncytial virus (RSV) cases in 2020 with those documented for the preceding four years.

methodsThis was a retrospective multicentric national survey study, driven by the Pediatric Spanish Society, and gathering monthly data from Spanish hospitals between 1st January 2016 and 31st December 2020. An Interrupted Time Series Analysis and Poisson regression models were performed for each index.

resultsThirty-eight hospitals representing most of the different regions of Spain participated. Compared to the preceding four years, in 2020, Pediatric emergency department visits significantly decreased immediately after initiation of the national lockdown. The median number of visits averted per month was 39,754 (IQR 26,539-50,065). RSV diagnoses during the 2020 winter season nearly disappeared with only 21 cases being documented among participating hospitals. The expected seasonal peak of bronchiolitis hospitalizations never occurred. The median number of admissions in 2020 averted per month was 100 (IQR 37-185) compared to 2016-2019. Only 3 hospitalized cases were RSV-confirmed. Reopening of schools and kindergarten was not associated with a remarkable increase in RSV cases or bronchiolitis hospitalizations.

conclusionA dramatic reduction of bronchiolitis admissions and near disappearance of RSV cases was observed in Spanish hospitals coinciding with the peak of the COVID-19 pandemic.

Indexed as

BronchiolitisCOVID-19Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsChildCommunicable Disease ControlHumansPandemicsRetrospective StudiesSARS-CoV-2SeasonsSpainBronchiolitis, viralCOVID-19InfectionRespiratory syncytial virusesRespiratory Tract

Identifiers

PMID34781241
PMCPMC8575537
OpenAlexW3211899426

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.