ArticleDrug and alcohol dependence2021
Wearable biosensors have the potential to monitor physiological changes associated with opioid overdose among people who use drugs: A proof-of-concept study in a real-world setting.
Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A wearable acoustofluidic patch for rapid reversal of opioid overdose.Nature communications · 2026Article
- Digital Technology Prediction of Anger, Aggression, and Violence: Recent Innovations and Methodological Considerations.Journal of interpersonal violence · 2026Article
- Acceptability and usability of a respiratory biosensor for drug overdose detection and first responder notification: a qualitative evaluation of perspectives from people who use drugs and wider stakeholders.Harm reduction journal · 2026Article
- Utilization and Feasibility of a Wearable Device in Patients With Sedative Effects of Drugs: Protocol for a Prospective Observational Study for the Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED) Study.JMIR research protocols · 2026Observational
- Use of a Shoulder-Mounted Wearable Sensor Prototype Designed to Detect Opioid-Related Overdose: A Qualitative User Experience Study.Journal of medical Internet research · 2025Article
- "It's something we're connected to": Acceptability and adoption of overdose detection technologies implemented in San Francisco permanent supportive housing.Journal of substance use and addiction treatment · 2025Article
- Article
- An autonomous implantable device for the prevention of death from opioid overdose.Science advances · 2024Article
- From Digital Inclusion to Digital Transformation in the Prevention of Drug-Related Deaths in Scotland: Qualitative Study.Journal of medical Internet research · 2024Article
- An Autonomous Implantable Device for the Prevention of Death from Opioid Overdose.bioRxiv : the preprint server for biology · 2024Article
- Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review.JMIR mHealth and uHealth · 2024Article
- Pharmacokinetics-Informed Neural Network for Predicting Opioid Administration Moments with Wearable Sensors.Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence · 2024Article
- Opioid Overdose Detection in a Murine Model Using a Custom-Designed Photoplethysmography Device.Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research · 2023Article
- Identifying biomarkers of drug use recurrence using wearable device technologies and phone applications.Drug and alcohol dependence · 2023Article
- Patient Engagement in a Multimodal Digital Phenotyping Study of Opioid Use Disorder.Journal of medical Internet research · 2023Article
- Between Care and Control: Examining Surveillance Practices in Harm Reduction.Contemporary drug problems · 2023Article
- Overdose Alert and Response Technologies: State-of-the-art Review.Journal of medical Internet research · 2023Review
- Overdose Detection Technologies to Reduce Solitary Overdose Deaths: A Literature Review.International journal of environmental research and public health · 2023Review
- Digital Biomarker Applications Across the Spectrum of Opioid Use Disorder.Cogent mental health · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
introductionWearable biosensors have the potential to monitor physiological change associated with opioid overdose among people who use drugs.
methodsWe enrolled 16 individuals who reported ≥ 4 daily opioid use events within the previous 30 day. Each was assigned a wearable biosensor that measured respiratory rate (RR) and actigraphy every 15 s for 5 days and also completed a daily interview assessing drug use. We describe the volume of RR data collected, how it varied by participant characteristics and drug use over time using repeated measures one-way ANOVA, episodes of acute respiratory depression (≤5 breaths/minute), and self-reported overdose experiences.
resultsWe captured 1626.4 h of RR data, an average of 21.7 daily hours/participant over follow-up. Individuals with longer injection careers and those engaging in polydrug use captured significantly fewer total hours of respiratory data over follow-up compared to those with shorter injections careers (94.7 vs. 119.9 h, p = 0.04) and injecting fentanyl exclusively (98.7 vs. 119.5 h, p = 0.008), respectively. There were 385 drug use events reported over follow-up. There were no episodes of acute respiratory depression which corresponded with participant reports of overdose experiences. DISCUSSION: Our preliminary findings suggest that using a wearable biosensor to monitor physiological changes associated with opioid use was feasible. However, more sensitive biosensors that facilitate triangulation of multiple physiological data points and larger studies of longer duration are needed.
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