Evidence map›Paper›PMID 34781096›Full record

ArticleDrug and alcohol dependence2021

Acceptability, feasibility, and pilot results of the tele-harm reduction intervention for rapid initiation of antiretrovirals among people who inject drugs.

Hansel E Tookes, Tyler S Bartholomew, Edward Suarez, Elisha Ekowo, Margaret Ginoza, David W Forrest, David P Serota, Allan Rodriguez, Michael A Kolber, Daniel J Feaster and 4 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  15. AIDS patient care and STDs · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hansel E TookesDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Tyler S BartholomewDepartment of Public Health Sciences, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA. Electronic address: tsb61@miami.edu.
Edward SuarezDepartment of Psychiatry, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Elisha EkowoDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Margaret GinozaDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
David W ForrestDepartment of Anthropology, University of Miami, 1320S Dixie Hwy, Coral Gables, FL 33146, USA.
David P SerotaDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Allan RodriguezDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Michael A KolberDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Daniel J FeasterDepartment of Public Health Sciences, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Angela MoossBehavioral Science Research Institute, 2600S Douglas Rd #712, Coral Gables, FL 33134, USA.
Derek BoydBehavioral Science Research Institute, 2600S Douglas Rd #712, Coral Gables, FL 33134, USA.
Candice SternbergDivision of Infectious Diseases, Department of Medicine, University of Miami, 1120 NW 14th St, Miami, FL 33136, USA.
Lisa R MetschDepartment of Sociomedical Sciences, Mailman School of Public Health, 2970 Broadway, New York, NY 10027, USA.

Funding

The Florida Node Alliance of the National Drug Abuse Treatment Clinical Trials NetworkUG1DA013720 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel J Feaster, Viviana Elizabeth Horigian · 2015 to 2026
$50.6M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel Bilbao · 2019 to 2026
$24.1M
A Multi-site Multi-Setting RCT of Integrated HIV Prevention and HCV Care for PWIDR01DA045713 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRUNEAU, JULIE, FEASTER, DANIEL J · 2017 to 2022
$8.2M
University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Training Program on HIV and Substance Use in the Criminal Justice SystemT32DA037801 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Nabila El-Bassel, Lisa R Metsch · 2014 to 2026
$5.7M
Tele-Harm Reduction for Rapid Initiation of Antiretrovirals in People who Inject Drugs: a Randomized Controlled TrialDP2DA053720 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI TOOKES, HANSEL EMORY · 2021 to 2024
$2.6M
NCI NIH HHS P30 CA240139NIAID NIH HHS P30 AI073961NIDA NIH HHS DP2 DA053720NIDA NIH HHS R01 DA045713NIDA NIH HHS T32 DA037801NIDA NIH HHS UG1 DA013720NIMH NIH HHS P30 MH116867
6 · The paper itself

Abstract

backgroundPeople who inject drugs (PWID) have been a marginalized and a stigmatized population since the beginning of the AIDS epidemic and have not experienced the same life-changing benefits of antiretroviral therapy as others. Tele-Harm Reduction (THR) is a telehealth-enhanced, harm reduction intervention, delivered within a trusted SSP venue. It aims to facilitate initiation of care and achieve rapid HIV viral suppression among PWID living with HIV.

methodsIn this mixed-methods study, we employed the Practical, Robust, Implementation and Sustainability Model (PRISM) implementation science framework to identify multilevel barriers and facilitators to implementing the THR intervention. Focus groups (n = 2, 16 participants), stakeholder interviews (n = 7) and in-depth interviews were conducted with PWID living with HIV (n = 25). In addition, to assess feasibility and acceptability, we pilot tested the THR intervention and reported viral suppression at 6 months.

resultsFocus groups and stakeholder interviews revealed system and organizational level barriers to implementation including requirements for identification and in person visits, waiting times, stigma, case management inexperience, multiple electronic health records, and billing. A potential facilitator was using telehealth for case management and initial provider visit. In the in depth interviews conducted with PWID living with HIV, participants expressed that the SSP creates a convenient, comfortable, confidential environment for delivering multiple, non-stigmatizing PWID-specific services. 35 PWID living with HIV were enrolled in the pilot study, 35 initiated antiretroviral therapy, and 25 (78.1%) were virally suppressed at six months.

conclusionRooted in harm reduction, the THR intervention shows promise in being an acceptable and feasible intervention that may facilitate engagement in HIV care and viral suppression among PWID.

Indexed as

Drug UsersHIV InfectionsSubstance Abuse, IntravenousFeasibility StudiesHarm ReductionHumansPilot ProjectsHarm reductionHIVPeople who inject drugsSyringe services programTelehealth

Identifiers

PMID34781096
PMCPMC9102418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.