Evidence map›Paper›PMID 34780821›Full record

ArticleThe Science of the total environment2022

SARS-CoV-2 monitoring at three sewersheds of different scales and complexity demonstrates distinctive relationships between wastewater measurements and COVID-19 case data.

M Nagarkar, S P Keely, M Jahne, E Wheaton, C Hart, B Smith, J Garland, E A Varughese, A Braam, B Wiechman and 2 more

Abstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  9. Dynamics of SARS-CoV-2 variants in southwest Ohio municipal wastewater.Environmental science : water research & technology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

M NagarkarOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Nagarkar.Maitreyi@epa.gov.
S P KeelyOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Keely.Scott@epa.gov.
M JahneOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Jahne.Michael@epa.gov.
E WheatonOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Wheaton.Emily@epa.gov.
C HartOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Hart.Chloe@epa.gov.
B SmithOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Smith.Bruce@epa.gov.
J GarlandOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Garland.Jay@epa.gov.
E A VarugheseOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Varughese.Eunice@epa.gov.
A BraamAPTIM Corp., 4171 Essen Lane, Baton Rouge, LA 70809. Electronic address: Braam.Ana@epa.gov.
B WiechmanAPTIM Corp., 4171 Essen Lane, Baton Rouge, LA 70809. Electronic address: Wiechman.Barry@epa.gov.
B MorrisPegasus Technical Services Inc., 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Morris.Brian@epa.gov.
N E BrinkmanOffice of Research and Development, United States Environmental Protection Agency, 26 W Martin Luther King Dr, Cincinnati, OH, USA. Electronic address: Brinkman.Nichole@epa.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater monitoring of SARS-CoV-2 presents a means of tracking COVID-19 community infection dynamics on a broader geographic scale. However, accounting for environmental and sample-processing losses may be necessary for wastewater measurements to readily inform our understanding of infection prevalence. Here, we present measurements of the SARS-CoV-2 N1 and N2 gene targets from weekly wastewater samples at three sites in Hamilton County, Ohio, during an increase and subsequent decline of COVID-19 infections. The concentration of N1 or N2 RNA in wastewater, measured over the course of six months, ranged from below the detection limit to over 10

Indexed as

COVID-19SARS-CoV-2HumansPrevalenceRNAWastewaterRNAWastewaterddPCREnvironmental surveillanceFecal indicatorsSARS-CoV-2Wastewater

Identifiers

PMID34780821
PMCPMC8590472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.