Evidence map›Paper›PMID 34780686›Full record

ArticleJournal of the American Chemical Society2021

Total Biosynthesis of the Tubulin-Binding Alkaloid Colchicine.

Ryan S Nett, Elizabeth S Sattely

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Discovery of pseudobaptigenin synthase in fungal-infected Trifolium pratense roots.The Plant journal : for cell and molecular biology · 2026
    Article
  5. Article
  6. Article
  7. Harnessing endophytes and Multi-Omics for sustainable Colchicine biosynthesis.World journal of microbiology & biotechnology · 2026
    Review
  8. Article
  9. Article
  10. At the roots of resistance.Nature chemical biology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Emerging functions within the enzyme families of plant alkaloid biosynthesis.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ryan S NettDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, United States.ORCID 0000-0002-2537-7010
Elizabeth S SattelyDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, United States.ORCID 0000-0002-7352-859X
Howard Hughes Medical Institute · US

Funding

Discovery and Engineering of Plant Natural Product PathwaysR01GM121527 · NIGMS · STANFORD UNIVERSITY · PI SATTELY, ELIZABETH SUSAN · 2017 to 2025
$2.3M
Computational appliance: a supercomputer for modern biomedical researchS10OD023452 · OD · STANFORD UNIVERSITY · PI DATTA, SOMALEE · 2017 to 2017
$600k
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM121527NIH HHS S10 OD023452
6 · The paper itself

Abstract

Colchicine (

Indexed as

ColchicineColchicumModels, MolecularMolecular StructureColchicine

Identifiers

PMID34780686
PMCPMC10824269
OpenAlexW3211794652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.