SynthesisAnesthesiology2022
Pain and Opioid Consumption and Mobilization after Surgery: Post Hoc Analysis of Two Randomized Trials.
Synthesis in Anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Efficacy and safety of ketamine in total hip arthroplasty: a systematic review.Journal of orthopaedic surgery and research · 2026Pooled it
- Efficacy of Erector Spinae Plane Block on Analgesic Outcomes in Patients Undergoing Metabolic Surgery: A Meta-Analysis of Randomized Controlled Trials.Obesity surgery · 2025Pooled it
- Effects of Early Mobilization Training on Mobility, Pain, Comfort, and Sleep Quality in Laparoscopic Abdominal Surgery Patients: A Randomized Controlled Trial.Clinical nursing research · 2026Trial
- Effect of a transfer- and ambulation-focused early mobilization protocol on functional capacity after kidney transplantation: a randomized controlled trial.BMC nephrology · 2026Trial
- Effect of progressive muscle relaxation on postoperative pain in laparoscopic living kidney donors: a randomized controlled trial.BMC surgery · 2025Trial
- Efficacy and safety of multidrug cocktail injections in postoperative pain management for lumbar microendoscopic decompression surgery: a prospective randomized controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Trial
- Efficacy of popliteal plexus block for opioid sparing and pain management after lower extremity surgery: a meta-analysis.The Korean journal of pain · 2026Article
- Popliteal plexus block: does opioid sparing translate into better recovery?The Korean journal of pain · 2026Article
- Educational Needs Analysis for Postoperative Early Ambulation Among Surgical-Ward Nurses and Patients: Using Borich Needs Assessment and Locus for Focus Models.Journal of clinical nursing · 2026Article
- Effect of Local Anesthetic-Eluting Foley Catheter (FreeFoley) on Urethral Pain and Discomfort After HoLEP: A Multicenter Prospective Controlled Study.European urology open science · 2026Article
- Oxycodone versus Sufentanil for Postoperative Analgesia and Early Recovery After Radical Gastrectomy: A Propensity Score-Matched Study.Drug design, development and therapy · 2026Article
- Association Between Early Postoperative Pain Burden and 30-Day Health-Related Quality of Life After Lumbar Spinal Fusion: A Multicenter Prospective Cohort Study.Journal of pain research · 2026Article
- Article
- Comparing Minimally Invasive and Conventional Approaches to DIEP Flap Harvest: A Matched-Pair Analysis from a High-Volume Center.Aesthetic plastic surgery · 2025Article
- Enhanced recovery and reduced opioid requirements following robot-assisted minimally invasive gastrectomy: a retrospective cohort study.Journal of robotic surgery · 2025Article
- From Steps to Mobility Levels: Validating a Consumer-Grade Activity Monitor for Automated Recording of Patient Mobility in Hospitals.Applied clinical informatics · 2025Article
- Development of the Korean enhanced recovery after surgery audit program.Scientific reports · 2025Observational
- Efficacy and Clinical Role of Rhomboid Intercostal Nerve Block for Postoperative Pain Management: a Narrative Review.Current pain and headache reports · 2025Review
- Efficacy of Erector Spinae Plane Block for Pain Management after Hip Surgery: A Narrative Review.Current pain and headache reports · 2025Review
- Association between acute pain trajectory and patient-reported outcomes at 6-months following lumbar surgery for patients with lumbar degenerative disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly mobilization is incorporated into many enhanced recovery pathways. Inadequate analgesia or excessive opioids may restrict postoperative mobilization. The authors tested the hypotheses that in adults recovering from abdominal surgery, postoperative pain and opioid consumption are inversely related to postoperative mobilization, and that postoperative mobilization is associated with fewer potentially related complications.
methodsThe authors conducted a subanalysis of two trials that enrolled adults recovering from abdominal surgery. Posture and movement were continuously monitored for 48 postoperative hours using noninvasive untethered monitors. Mobilization was defined as the fraction of monitored time spent sitting or standing.
resultsA total of 673 patients spent a median [interquartile range] of 7% [3 to 13%] of monitored time sitting or standing. Mobilization time was 1.9 [1.0 to 3.6] h/day for patients with average pain scores 3 or lower, but only 1.2 [0.5 to 2.6] h/day in those with average scores 6 or greater. Each unit increase in average pain score was associated with a decrease in mobilization time of 0.12 (97.5% CI, 0.02 to 0.24; P = 0.009) h/day. In contrast, there was no association between postoperative opioid consumption and mobilization time. The incidence of the composite of postoperative complications was 6.0% (10 of 168) in the lower mobilization quartile, 4.2% (7 of 168) in the second quartile, and 0% among 337 patients in the highest two quartiles (P = 0.009).
conclusionsPatients recovering from abdominal surgery spent only 7% of their time mobilized, which is considerably less than recommended. Lower pain scores are associated with increased mobility, independently of opioid consumption. Complications were more common in patients who mobilized poorly. EDITOR’S PERSPECTIVE:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.