Evidence map›Paper›PMID 34780276›Full record

ArticleInfection and immunity2022

Conserved Tandem Arginines for PbgA/YejM Allow Salmonella Typhimurium To Regulate LpxC and Control Lipopolysaccharide Biogenesis during Infection.

Nicole P Giordano, Joshua A Mettlach, Zachary D Dalebroux

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Signaling through theJournal of bacteriology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicole P GiordanoDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Centergrid.266902.9, Oklahoma City, Oklahoma, USA.
Joshua A MettlachDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Centergrid.266902.9, Oklahoma City, Oklahoma, USA.
Zachary D DalebrouxDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Centergrid.266902.9, Oklahoma City, Oklahoma, USA.ORCID 0000-0001-9348-2894
University of Oklahoma Health Sciences Center · US

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Mark L Lang · 2012 to 2026
$60.2M
Molecular Basis of Immunity - Kirschtein-NRSAT32AI007633 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CUNNINGHAM, MADELEINE W. · 2001 to 2022
$4.0M
Mechanisms of PbgA involvement in Salmonella Typhimurium lipid homeostasis for bacterial pathogenesisR01AI139248 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI DALEBROUX, ZACHARY DAVID · 2018 to 2022
$1.8M
NIAID NIH HHS R01 AI139248NIAID NIH HHS T32 AI007633NIGMS NIH HHS P20 GM103447
6 · The paper itself

Abstract

Enterobacteriaceae use the periplasmic domain of the conserved inner membrane protein, PbgA/YejM, to regulate lipopolysaccharide (LPS) biogenesis. Salmonella enterica serovar Typhimurium (

Indexed as

Escherichia coli ProteinsAmidohydrolasesAnimalsArginineEscherichia coliLipid ALipopolysaccharidesMembrane ProteinsMiceSalmonella typhimuriumAmidohydrolasesArginineEscherichia coli ProteinsLipid ALipopolysaccharidesMembrane ProteinsYciM protein, E coliYejM protein, E colibacteremiabacterial membranecore oligosaccharideFtsHLapB/YciMlipid Alipid regulationlipid remodelinglipopolysaccharideLPSLpxCnon-typhoidalO-antigenouter membranePbgA/YejMproteaseproteolysis

Identifiers

PMID34780276
PMCPMC8853683
OpenAlexW3211860735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.