Evidence map›Paper›PMID 34780273›Full record

ArticleAntimicrobial agents and chemotherapy2022

Impact of

Dipti Sharma, Raees A Paul, Shivaprakash M Rudramurthy, Nisha Kashyap, Sanjay Bhattacharya, Rajeev Soman, Shamanth A Shankarnarayan, Dipali Chavan, Shreya Singh, Parijit Das and 5 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. JAC-antimicrobial resistance · 2026
    Article
  5. Genomic landscape ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  6. Deciphering the multidrug resistance paradigm inAntimicrobial agents and chemotherapy · 2026
    Review
  7. ER stress selects forFrontiers in microbiology · 2026
    Article
  8. Frontiers in cellular and infection microbiology · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. First Report ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Article
  15. A benchmark dataset for validatingMicrobiology spectrum · 2025
    Article
  16. Review
  17. Trends in Antifungal Resistance AmongJournal of fungi (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Emergence of multidrug-resistantFrontiers in microbiology · 2025
    Article
  20. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Dipti Sharma *Department of Medical Microbiology, PGIMER, Chandigarh, India.
Raees A Paul *Department of Medical Microbiology, PGIMER, Chandigarh, India.
Shivaprakash M RudramurthyDepartment of Medical Microbiology, PGIMER, Chandigarh, India.ORCID 0000-0002-9097-9253
Nisha KashyapDepartment of Medical Microbiology, PGIMER, Chandigarh, India.
Sanjay BhattacharyaTata Medical Centre, Kolkata, India.
Rajeev SomanJupiter Hospital, Pune, India.
Shamanth A ShankarnarayanDepartment of Medical Microbiology, PGIMER, Chandigarh, India.
Dipali ChavanJupiter Hospital, Pune, India.
Shreya SinghDepartment of Medical Microbiology, PGIMER, Chandigarh, India.
Parijit DasTata Medical Centre, Kolkata, India.
Harsimran KaurDepartment of Medical Microbiology, PGIMER, Chandigarh, India.
Anup K GhoshDepartment of Medical Microbiology, PGIMER, Chandigarh, India.ORCID 0000-0002-0341-6680
Rajendra PrasadAmity Institute of Biotechnology & Integrative Sciences and Health, Amity University Haryana, Gurgaon, India.
Kaustuv SanyalJawaharlal Nehru Center for Advanced Scientific Research, Bengaluru, India.ORCID 0000-0002-6611-4073
Arunaloke ChakrabartiDepartment of Medical Microbiology, PGIMER, Chandigarh, India.ORCID 0000-0003-1555-3807
Post Graduate Institute of Medical Education and Research · INTata Medical Center · INJawaharlal Nehru Centre for Advanced Scientific Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echinocandins are frontline antifungal agents in the management of invasive infections due to multidrug resistant Candida auris. The study aimed to evaluate echinocandin resistance in C. auris isolates of multicentric origin, identify the resistance mechanism, and analyze the pharmacodynamic response to caspofungin in a neutropenic mouse model of infection. A total of 199 C. auris isolates originating from 30 centers across India were tested for susceptibility to echinocandins. Isolates with reduced susceptibility were evaluated for

Indexed as

Antifungal AgentsCandida aurisDrug Resistance, FungalEchinocandinsFungal ProteinsAnimalsCandidiasisDisease Models, AnimalGenotypeMiceMicrobial Sensitivity TestsMutationAntifungal AgentsEchinocandinsFungal ProteinsCandida aurischitinechinocandinsFKS1FKS mutationmurine modelpharmacodynamicsresistance

Identifiers

PMID34780273
PMCPMC8765266
OpenAlexW3214482667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.