Evidence map›Paper›PMID 34780122›Full record

ArticleClinical and translational science2022

Limited sampling strategies for estimation of tacrolimus exposure in kidney transplant recipients receiving extended-release tacrolimus preparation.

Toqa El-Nahhas, Joyce Popoola, Iain MacPhee, Atholl Johnston

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Tacrolimus-why pharmacokinetics matter in the clinic.Frontiers in transplantation · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Toqa El-NahhasDepartment of Clinical Pharmacology, Barts and the London, School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Joyce PopoolaInstitute of Medical and Biomedical Education, St. George's, University of London, London, UK.
Iain MacPheeInstitute of Medical and Biomedical Education, St. George's, University of London, London, UK.
Atholl JohnstonDepartment of Clinical Pharmacology, Barts and the London, School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Queen Mary University of London · GBSt George’s University Hospitals NHS Foundation Trust · GB

Funding

Chiesi LTD
6 · The paper itself

Abstract

Tacrolimus is the key component of most contemporary immunosuppressive drug regimens for the prevention of transplant rejection. Area under the concentration time curve over 24 h (AUC

Indexed as

Kidney TransplantationAdultFemaleHumansImmunosuppressive AgentsLinear ModelsMaleMiddle AgedTacrolimusImmunosuppressive AgentsTacrolimus

Identifiers

PMID34780122
PMCPMC8742643
OpenAlexW3212176386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.