Evidence map›Paper›PMID 34779920›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Symptom burden, psychological distress, and health-related quality of life in cancer survivors with pelvic late radiation tissue injuries.

Grete K Velure, Bernd Müller, May Aa Hauken

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03570229 (Pelvic Radiation Injuries After Cancer Treatment), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03570229 completednot on this map

Pelvic Radiation Injuries After Cancer Treatment: Symptoms, Quality of Life and Experiences Before, Along and After Hyperbaric Oxygenation Treatment

TypeobservationalSponsorUniversity of BergenRan2018 to 2022Enrolled137ConditionsCancerArmsHyperbaric oxygen treatment
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. The psychological distress of gastrointestinal cancer patients and its association with quality of life among different genders.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  7. Article
  8. Article
  9. Symptom burden and health-related quality of life six months after hyperbaric oxygen therapy in cancer survivors with pelvic radiation injuries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Grete K VelureCentre for Crisis Psychology, Faculty of Psychology, University of Bergen, Møllendalsbakken 9, N - 5009, Bergen, Norway. grete.velure@helse-bergen.no.ORCID http://orcid.org/0000-0002-8252-7134
Bernd MüllerCentre for Crisis Psychology, Faculty of Psychology, University of Bergen, Møllendalsbakken 9, N - 5009, Bergen, Norway.
May Aa HaukenCentre for Crisis Psychology, Faculty of Psychology, University of Bergen, Møllendalsbakken 9, N - 5009, Bergen, Norway.ORCID http://orcid.org/0000-0003-0538-2848
Haukeland University Hospital · NOUniversity of Bergen · NO

Funding

dam foundation (priviously named ekstrastiftelsen helse og rehabilitering) and the norwegian gyanecological cancer society 2019/FO244488
6 · The paper itself

Abstract

purposeCurative radiotherapy for cancer may lead to severe late radiation tissue injuries (LRTIs). However, limited knowledge exists about pelvic cancer survivors' LRTI symptoms, distress, and health-related quality of life (HRQOL). We sought to assess the symptom burden, distress, and HRQOL in survivors with established pelvic LRTIs compared to norm populations and to investigate the relation between these factors.

methodsCancer survivors referred for treatment of established pelvic LRTIs were recruited nationwide. LTRIs were assessed with the Expanded Prostate Cancer Index Composite (EPIC), psychological distress was assessed with the General Health Questionnaire (GHQ-12), and HRQOL was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORCT-QLQ-C30).

resultsA total of 107 participants (mean age 64, 53% men) were included. Compared to norms, participants reported more urinary (mean 68.7 vs. 89.5; p = 0.00; d = 1.4) and bowel symptoms (mean 62.5 vs. 92.4; p = 0.00; d = 2.7), increased psychological distress (mean 13.4 vs. 10.3; p = 0.00; d = 0.6), and overall poorer HRQOL (mean 54.9 vs. 71.2; p = 0.00; d = 0.7). Higher symptom burden and higher levels of psychological distress were associated with lower HRQOL (r

conclusionCancer survivors with established pelvic LRTIs are highly burdened compared to norms. The association of the LRTI-related symptom burden with HRQOL is independent of the level of psychological distress. Both coping and treatment interventions are crucial to promoting long-term health and HRQOL.

trial registrationNCT03570229.

Indexed as

Cancer SurvivorsNeoplasmsPsychological DistressFemaleHumansMaleMiddle AgedQuality of LifeSurveys and QuestionnairesSurvivorsLate effectsLong-term survivorsPelvic malignanciesPelvic radiotherapyPsychological distressQuality of life

Identifiers

PMID34779920
PMCPMC8794896
OpenAlexW3213282301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.