Evidence map›Paper›PMID 34779877›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Hit-and-run: a Swedish nationwide cohort study of serious transport accidents and convictions due to traffic offenses in obsessive-compulsive disorder.

David Mataix-Cols, Lorena Fernández de la Cruz, Gustaf Brander, Erik Andersson, Brian M D'Onofrio, Christian Rück, Henrik Larsson, Paul Lichtenstein, Anna Sidorchuk

Open access · hybridAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

David Mataix-ColsDepartment of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden. david.mataix.cols@ki.se.ORCID http://orcid.org/0000-0002-4545-0924
Lorena Fernández de la CruzDepartment of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
Gustaf BranderDepartment of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
Erik AnderssonDivision of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Brian M D'OnofrioDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Christian RückDepartment of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Anna SidorchukDepartment of Clinical Neuroscience, Child and Adolescent Psychiatry Research Centre, Karolinska Institutet, Gävlegatan 22B, 8th floor, 113 30 , Stockholm, Sweden.
Karolinska Institutet · SEÖrebro University · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIndividuals with obsessive-compulsive disorder (OCD) often report driving-related obsessions, such as fears of causing accidents, but the risk of transport accidents in OCD is unknown. We investigated whether individuals with OCD have an increased risk of serious transport accidents and convictions due to traffic offenses and explored the role of psychiatric comorbidities.

methodsWe included all individuals ≥ 18 years living in Sweden between 1997 and 2013 (N = 5,760,734). A total of 23,126 individuals had a diagnosis of OCD in the National Patient Register. We also identified 16,607 families with full siblings discordant for OCD. Cox proportional hazards regression models estimated hazard ratios (HRs) with 95% confidence intervals (CIs) for the risk of three outcomes in individuals with OCD, compared to unexposed individuals and their unexposed full siblings: injuries or deaths due to transport accidents, injuries or deaths due to motor vehicle accidents, and convictions related to traffic offenses. Psychiatric comorbidities were systematically adjusted for.

resultsWomen, but not men, with OCD had a marginally increased risk of serious transport accidents (adjusted HR = 1.20 [95% CI 1.13-1.28]) and motor vehicle accidents (adjusted HR = 1.20 [95% CI 1.09-1.31]), compared to unaffected individuals. Neither women nor men with OCD had a significantly increased risk of convictions. The sibling comparisons showed no significant associations. When psychiatric comorbidities were adjusted for, several observed associations became non-significant or inversed (HRs and 95% CIs below one).

conclusionThe risks of serious transport accidents and driving-related criminal convictions in OCD are negligible and heavily influenced by psychiatric comorbidity.

Indexed as

Obsessive-Compulsive DisorderCohort StudiesComorbidityFemaleHumansSiblingsSwedenAccidentsInjuriesMortalityMotor vehiclesObsessive–compulsive disorderTraffic

Identifiers

PMID34779877
PMCPMC9375758
OpenAlexW3214400445

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.