Evidence map›Paper›PMID 34779243›Full record

ArticleJournal of the American Heart Association2021

Direct Oral Anticoagulant Adherence of Patients With Atrial Fibrillation Transitioned from Warfarin.

Krishna N Pundi, Alexander C Perino, Jun Fan, Susan Schmitt, Mitra Kothari, Karolina Szummer, Mariam Askari, Paul A Heidenreich, Mintu P Turakhia

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Standard-Intensity Versus Low-Intensity Anticoagulation with Warfarin in Asian Patients with Atrial Fibrillation: A Multi-Center, Randomized Controlled Trial.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Krishna N PundiDepartment of Medicine Stanford University School of Medicine Stanford CA.ORCID 0000-0002-1230-367X
Alexander C PerinoDepartment of Medicine Stanford University School of Medicine Stanford CA.ORCID 0000-0001-5482-8055
Jun FanVeterans Affairs Palo Alto Health Care System Palo Alto CA.
Susan SchmittVeterans Affairs Palo Alto Health Care System Palo Alto CA.
Mitra KothariVeterans Affairs Palo Alto Health Care System Palo Alto CA.ORCID 0000-0003-3330-6279
Karolina SzummerDepartment of Medicine Stanford University School of Medicine Stanford CA.
Mariam AskariVeterans Affairs Palo Alto Health Care System Palo Alto CA.
Paul A HeidenreichDepartment of Medicine Stanford University School of Medicine Stanford CA.ORCID 0000-0001-7730-8490
Mintu P TurakhiaDepartment of Medicine Stanford University School of Medicine Stanford CA.ORCID 0000-0001-8025-0904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Reduced time in international normalized ratio therapeutic range (TTR) limits warfarin safety and effectiveness. In patients switched from warfarin to direct oral anticoagulants (DOACs), patient factors associated with low TTR could also increase risk of DOAC nonadherence. We investigated the relationship between warfarin TTR and DOAC adherence in warfarin-treated patients with atrial fibrillation switched to DOAC. Methods and Results Using data from the Veterans Health Administration, we identified patients with atrial fibrillation switched from warfarin to DOAC (switchers) or treated with warfarin alone (non-switchers). Logistic regression was used to evaluate association between warfarin TTR and DOAC adherence. We analyzed 128 605 patients (age, 71±9; 1.6% women; CHA

Indexed as

AnticoagulantsAtrial FibrillationDrug MonitoringAdministration, OralAgedAged, 80 and overFemaleHumansMaleMiddle AgedWarfarinAnticoagulantsWarfarinanticoagulationatrial fibrillation heartwarfarin

Identifiers

PMID34779243
PMCPMC9075386

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.