Evidence map›Paper›PMID 34779225›Full record

ArticleJournal of the American Heart Association2021

Manual Thrombus Aspiration and its Procedural Stroke Risk in Myocardial Infarction.

Yohei Sotomi, Yasunori Ueda, Shungo Hikoso, Daisaku Nakatani, Shinichiro Suna, Tomoharu Dohi, Hiroya Mizuno, Katsuki Okada, Hirota Kida, Bolrathanak Oeun and 9 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Thrombus Aspiration: Is It the Art or the Science?Journal of the American Heart Association · 2021
    Article
  10. Review
  11. AngioJet Rheolytic Thrombectomy Combined with Glycoprotein IIb/IIIa Inhibitors in Acute Myocardial Infarction: An Observational Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Yohei SotomiDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Yasunori UedaCardiovascular Division National Hospital Organization Osaka National Hospital Osaka Japan.
Shungo HikosoDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0003-2284-1970
Daisaku NakataniDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Shinichiro SunaDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Tomoharu DohiDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Hiroya MizunoDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Katsuki OkadaDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Hirota KidaDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Bolrathanak OeunDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Akihiro SunagaDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Taiki SatoDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Sciences Department of Social and Environmental Medicine Graduate School of Medicine Osaka University Osaka Japan.
Yasuhiko SakataDepartment of Clinical Medicine and Development and Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.
Hiroshi SatoSchool of Human Welfare Studies Health Care Center and Clinic Kwansei Gakuin University Hyogo Japan.ORCID 0000-0003-1033-4824
Masatsugu HoriOsaka International Cancer Institute Osaka Japan.
Issei KomuroDepartment of Cardiovascular Medicine University of Tokyo Graduate School of Medicine Tokyo Japan.ORCID 0000-0002-0714-7182
Yasushi SakataDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0002-5618-4721
Osaka Acute Coronary Insufficiency Study (OACIS) Group
The University of Osaka · JPNational Cerebral and Cardiovascular Center · JPKwansei Gakuin University · JPOsaka International Cancer Institute · JPOsaka National Hospital · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The previous large-scale randomized controlled trial showed that routine thrombus aspiration (TA) during percutaneous coronary intervention (PCI) was associated with an increased risk of stroke. However, real-world clinical evidence is still limited. Methods and Results We investigated the association between manual TA and stroke risk during primary PCI in the OACIS (Osaka Acute Coronary Insufficiency Study) database (N=12 093). The OACIS is a prospective, multicenter registry of myocardial infarction. The primary end point of the present study is stroke at 7 days. A total of 9147 patients who underwent primary PCI within 24 hours of hospitalization were finally analyzed (TA group, n=4448, versus non-TA group, n=4699 patients). TA was independently associated with risk of stroke at 7 days (odds ratio [OR], 1.92 [95% CI, 1.19‒3.12];

Indexed as

Myocardial InfarctionPercutaneous Coronary InterventionStrokeThrombosisCoronary ThrombosisHumansProspective StudiesThrombectomyTreatment Outcomeacute myocardial infarctionpercutaneous coronary interventionstrokethrombus aspiration

Identifiers

PMID34779225
PMCPMC8751963
OpenAlexW3213654966

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.