ArticleJournal of the American Heart Association2021
Atrial Fibrillation in Patients With Cardiomyopathy: Prevalence and Clinical Outcomes From Real-World Data.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Evidence for a role of adverse sarcomere signaling in atrial fibrillation induction.Journal of molecular and cellular cardiology plus · 2026Review
- Complication management in hypertrophic cardiomyopathy.Heart failure reviews · 2026Review
- Prevalence of atrial fibrillation and associated factors among adult cardiac patients at Ambo University Referral Hospital, West Shewa, Ethiopia, 2024/2025.American heart journal plus : cardiology research and practice · 2026Article
- Perspectives on phenotype in genetic testing for early-onset atrial fibrillation.European journal of human genetics : EJHG · 2026Article
- Causal atlas on comorbidities in cardiomyopathy: a Mendelian randomization study of European ancestry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Predictive Value of Preoperative Left Atrial Coupling Indices for Postoperative Atrial Fibrillation After Isolated CABG.Medicina (Kaunas, Lithuania) · 2026Article
- First-pass isolation and procedural metrics associated with catheter ablation outcomes for atrial fibrillation: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Walras modulates sex-dependent endoplasmic reticulum stress in cardiomyopathy.Frontiers in physiology · 2026Article
- Effect of sarcopenia on risk of atrial fibrillation: a systematic review and meta-analysis of observational studies.Frontiers in cardiovascular medicine · 2026Review
- Long-Term Outcomes of Drug-Refractory Atrial Fibrillation After Atrioventricular Node Ablation Combined with Implantation of a Cardiac Resynchronization Therapy Defibrillator (CRT-D).Journal of clinical medicine · 2025Article
- Risk of cancer following presentation with new-onset atrial fibrillation using data from UK national databases.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Mortality Trends in Atrial Fibrillation With Cardiomyopathy Among Patients Aged 25 and Older in the United States.Pacing and clinical electrophysiology : PACE · 2025Article
- Endothelial Cell-Related Proteins in Plasma Predict Major Adverse Cardiovascular Events and Worsening Heart Failure in Patients With Hypertrophic Cardiomyopathy.Journal of the American Heart Association · 2025Article
- Predicting arrhythmia recurrence post-ablation in atrial fibrillation using explainable machine learning.Communications medicine · 2025Article
- Missense variants in the myosin binding domains ofbioRxiv : the preprint server for biology · 2025Article
- Stroke in Dilated Cardiomyopathy: An Autopsy-Based Study of Mechanisms, Topography, and Clinical Implications.Diagnostics (Basel, Switzerland) · 2025Article
- Cardiovascular disease reported as modes of death in the Office for National Statistics mortality data: a retrospective observational study.JRSM open · 2025Article
- Global use of angiotensin receptor neprilysin inhibitor in heart failure and reduced, below normal and supranormal ejection fraction.Heart and vessels · 2025Observational
- Glucagon-like peptide-1 receptor agonists improve outcomes in individuals with type 2 diabetes with and without heart failure.International journal of cardiology · 2025Article
- Innovative approaches to atrial fibrillation prediction: should polygenic scores and machine learning be implemented in clinical practice?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Cardiomyopathy is a common cause of atrial fibrillation (AF) and may also present as a complication of AF. However, there is a scarcity of evidence of clinical outcomes for people with cardiomyopathy and concomittant AF. The aim of the present study was therefore to characterize the prevalence of AF in major subtypes of cardiomyopathy and investigate the impact on important clinical outcomes. Methods and Results A retrospective cohort study was conducted using electronic medical records from a global federated health research network, with data primarily from the United States. The TriNetX network was searched on January 17, 2021, including records from 2002 to 2020, which included at least 1 year of follow-up data. Patients were included based on a diagnosis of hypertrophic, dilated, or restrictive cardiomyopathy and concomitant AF. Patients with cardiomyopathy and AF were propensity-score matched for age, sex, race, and comorbidities with patients who had a cardiomyopathy only. The outcomes were 1-year mortality, hospitalization, incident heart failure, and incident stroke. Of 634 885 patients with cardiomyopathy, there were 14 675 (2.3%) patients with hypertrophic, 90 117 (7.0%) with restrictive, and 37 685 (5.9%) with dilated cardiomyopathy with concomitant AF. AF was associated with significantly higher odds of all-cause mortality (odds ratio [95% CI]) for patients with hypertrophic (1.26 [1.13-1.40]) and dilated (1.36 [1.27-1.46]), but not restrictive (0.98 [0.94-1.02]), cardiomyopathy. Odds of hospitalization, incident heart failure, and incident stroke were significantly higher in all cardiomyopathy subtypes with concomitant AF. Among patients with AF, catheter ablation was associated with significantly lower odds of all-cause mortality at 12 months across all cardiomyopathy subtypes. Conclusions Findings of the present study suggest AF may be highly prevalent in patients with cardiomyopathy and associated with worsened prognosis. Subsequent research is needed to determine the usefulness of screening and multisdisciplinary treatment of AF in this population.
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